DRSC/TRiP Functional Genomics Resources

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Protein Alignment TYRO3 and dpr16

DIOPT Version :9

Sequence 1:NP_006284.2 Gene:TYRO3 / 7301 HGNCID:12446 Length:890 Species:Homo sapiens
Sequence 2:NP_001287169.1 Gene:dpr16 / 40619 FlyBaseID:FBgn0037295 Length:488 Species:Drosophila melanogaster


Alignment Length:265 Identity:55/265 - (20%)
Similarity:82/265 - (30%) Gaps:87/265 - (32%)


- Green bases have known domain annotations that are detailed below.


Human    34 LLPESAAAGLKLMGAPVKLTVSQGQPVKLNCSVEGMEEPDIQWV-------------------KD 79
            |||..     :|...|:..||..||...|.|.:.......:.||                   :.
  Fly   195 LLPRR-----QLSLPPLNATVQAGQHAYLPCKLNQHSGKPLSWVRLRDEHIIAVDHTTFINDARF 254

Human    80 GAVVQN-----------LDQLYIPV--------------------SEQHWIGFLSLKSVERSDAG 113
            .:::|:           |.....||                    |...|.  |.:|.|...|||
  Fly   255 ASLLQSTTLTTLVSGGALSTTATPVAALGNSFAHAVPGGQERGNSSSLSWT--LQIKYVNLEDAG 317

Human   114 RYWCQVEDGGETEISQPVWLTVEGVPFFTVEPKDLAVPPNAPF-------QLSCEAVGPPE-PVT 170
            .|.||:  ..|.::|..|.|       |.:.|:...:.....|       :|.|...|..| |..
  Fly   318 WYECQL--ATEPKMSAKVQL-------FVITPRTELIGDRQRFVKAGSRVELHCIVRGTLEAPKY 373

Human   171 IVWWRGTTKIGGPAPSPSVLNVTGVTQSTMFSCEAHNLKGLASSRTATVHLQALPAAPFNITVTK 235
            |.|:||..::       :..|.....||..::....|:.|.......|:....:|      .|.|
  Fly   374 IFWYRGDQQV-------TAENEASGAQSGWYTQIDRNIFGSTEHNRNTIGSLVIP------LVRK 425

Human   236 LSSSN 240
            :.|.|
  Fly   426 IHSGN 430

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TYRO3NP_006284.2 IG_like 49..135 CDD:214653 28/135 (21%)
IGc2 56..121 CDD:197706 21/114 (18%)
Ig2_Tyro3_like 141..220 CDD:143226 18/86 (21%)
IG_like 145..220 CDD:214653 17/82 (21%)
FN3 225..317 CDD:238020 5/16 (31%)
fn3 324..406 CDD:278470
PTKc_Tyro3 508..791 CDD:270659
Pkinase_Tyr 518..786 CDD:285015
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 815..837
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 851..871
dpr16NP_001287169.1 IG_like 205..337 CDD:214653 28/142 (20%)
Ig <298..338 CDD:299845 16/50 (32%)
IG_like 352..447 CDD:214653 20/92 (22%)
Ig 358..439 CDD:143165 20/86 (23%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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