DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment TYRO3 and DIP-eta

DIOPT Version :9

Sequence 1:NP_006284.2 Gene:TYRO3 / 7301 HGNCID:12446 Length:890 Species:Homo sapiens
Sequence 2:NP_001188701.2 Gene:DIP-eta / 33793 FlyBaseID:FBgn0031725 Length:450 Species:Drosophila melanogaster


Alignment Length:207 Identity:51/207 - (24%)
Similarity:79/207 - (38%) Gaps:47/207 - (22%)


- Green bases have known domain annotations that are detailed below.


Human    52 LTVSQGQPVKLNCSVEGMEEPDIQWVKDGAV---------VQNLD--QLYIPVSEQHWIGFLSLK 105
            :.|.:|..|.|.|:..|..||.|.|.::..|         |.:::  .|.||             
  Fly   156 MVVREGSNVTLKCAATGSPEPTITWRRESGVPIELATGEEVMSIEGTDLVIP------------- 207

Human   106 SVERSDAGRYWCQVEDGGETEISQPVWLTVEGVPFFTVEPKDLAVPPNAPFQLSCEAVGPPEPVT 170
            :|.|...|.|.|...:|....:|:.:.|.|...|..||:.:.:.........|.||:...|:  :
  Fly   208 NVRRHHMGAYLCIASNGVPPSVSKRITLVV
HFPPMITVQNQLIGAVEGKGVTLDCESEAYPK--S 270

Human   171 IVWW---RG------------TTKIGGPAPSPSVLNVTGVTQSTM--FSCEAHNLKGLASSRTAT 218
            |.:|   ||            .|:|||...|.. |::..:||:..  :.|.|.|..|   ....|
  Fly   271 INYWTRERGEIVPPGGKYSANVTEIGGYRNSMR-LHINPLTQAEFGSYRCVAKNSLG---DTDGT 331

Human   219 VHLQALPAAPFN 230
            :.|..:|....|
  Fly   332 IKLY
RIPPNAVN 343

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TYRO3NP_006284.2 IG_like 49..135 CDD:214653 23/93 (25%)
IGc2 56..121 CDD:197706 19/75 (25%)
Ig2_Tyro3_like 141..220 CDD:143226 23/95 (24%)
IG_like 145..220 CDD:214653 21/91 (23%)
FN3 225..317 CDD:238020 2/6 (33%)
fn3 324..406 CDD:278470
PTKc_Tyro3 508..791 CDD:270659
Pkinase_Tyr 518..786 CDD:285015
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 815..837
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 851..871
DIP-etaNP_001188701.2 Ig 51..141 CDD:299845
IG_like 51..137 CDD:214653
IG_like 153..237 CDD:214653 23/93 (25%)
Ig 161..224 CDD:299845 19/75 (25%)
IG_like 252..335 CDD:214653 21/88 (24%)
Ig 258..333 CDD:143165 21/80 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.