DRSC/TRiP Functional Genomics Resources

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Protein Alignment TYRO3 and dpr3

DIOPT Version :9

Sequence 1:NP_006284.2 Gene:TYRO3 / 7301 HGNCID:12446 Length:890 Species:Homo sapiens
Sequence 2:NP_001014459.2 Gene:dpr3 / 3346208 FlyBaseID:FBgn0053516 Length:522 Species:Drosophila melanogaster


Alignment Length:159 Identity:37/159 - (23%)
Similarity:62/159 - (38%) Gaps:44/159 - (27%)


- Green bases have known domain annotations that are detailed below.


Human    47 GAPVKLTVSQGQ-PVKLNCSVEGMEEPDIQWVKD--------GAVVQNLDQLYIPVSE----QHW 98
            |.|..:|...|. ...:.|.|:.:.:..:.|::.        |......|:.: .|:|    :.|
  Fly   241 GMPRNITGRTGHTEAIIKCRVDSLHDKSVSWIRKRDLHILTVGTATYTSDKRF-QVTESKDSREW 304

Human    99 IGFLSLKSVERSDAGRYWCQVEDGGETEISQPVWLTVEGVPFFTVEPKDLAV---PPNAPFQ--- 157
            .  |.:|:....|:|.|.|||..  |.::|....|.:     ..:.|...||   ||:..|:   
  Fly   305 T--LHVKAPLAKDSGIYECQVNT--EPKMSMAFQLNI-----IEISPDAKAVISGPPDLHFKAGS 360

Human   158 ---LSC-------EAVGPPEPVTIVWWRG 176
               |:|       :.:||     |.|:||
  Fly   361 AIILNCLVQQPSVKDIGP-----IYWYRG 384

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TYRO3NP_006284.2 IG_like 49..135 CDD:214653 22/98 (22%)
IGc2 56..121 CDD:197706 17/77 (22%)
Ig2_Tyro3_like 141..220 CDD:143226 14/52 (27%)
IG_like 145..220 CDD:214653 14/48 (29%)
FN3 225..317 CDD:238020
fn3 324..406 CDD:278470
PTKc_Tyro3 508..791 CDD:270659
Pkinase_Tyr 518..786 CDD:285015
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 815..837
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 851..871
dpr3NP_001014459.2 Ig 243..330 CDD:299845 20/91 (22%)
IG_like 243..329 CDD:214653 20/90 (22%)
Ig 350..464 CDD:299845 11/40 (28%)
IG_like <441..477 CDD:214653
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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