DRSC/TRiP Functional Genomics Resources

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Protein Alignment TYRO3 and dpr9

DIOPT Version :9

Sequence 1:NP_006284.2 Gene:TYRO3 / 7301 HGNCID:12446 Length:890 Species:Homo sapiens
Sequence 2:NP_001287332.1 Gene:dpr9 / 2768670 FlyBaseID:FBgn0038282 Length:602 Species:Drosophila melanogaster


Alignment Length:356 Identity:85/356 - (23%)
Similarity:131/356 - (36%) Gaps:83/356 - (23%)


- Green bases have known domain annotations that are detailed below.


Human    32 SLLLPESAAAGLKLMGAPVK-LTVSQGQPVKLNCSVEGMEEP----DIQWVKD--------GAVV 83
            |:.|.|:..||.....|..| :|...|:...|||.|:.:...    .:.||:.        |...
  Fly   245 SIDLEEARNAGPYFDKAFSKNVTALLGKTAYLNCRVKNLGNKTMLLQVSWVRHRDIHLLTVGRYT 309

Human    84 QNLDQLYIPVSE---QHWIGFLSLKSVERSDAGRYWCQVEDGGETEISQPVWLTVEGVPFFTVEP 145
            ...||.:..:.:   :.|:  |.:|..:..|:|.|.|||..  ...:|..:.|.|       |||
  Fly   310 YTSDQRFRAIHQPQTEDWM--LQIKYPQHRDSGIYECQVST--TPHMSHYIHLNV-------VEP 363

Human   146 K-------DLAVPPNAPFQLSCEAVGPPEPVTIVWWRGTTKIGGPAPS-PSVLNVT----GVTQS 198
            .       ||.:...:...|:|.....|||...::|......    || |.::|..    ||:..
  Fly   364 STEIIGAPDLYIESGSTINLTCIIQNSPEPPAYIFWNHNNAF----PSHPQIINYDSPRGGVSVV 424

Human   199 TMFSCEAHNLKGLASSRTA-TVHLQALP--AAPFNITVTKLSSSNASVAWMPGADGRALLQSCTV 260
            |.......:...:.|:|.: :.|.|..|  |.|.::||..|:..:.||:       |.:..|...
  Fly   425 TNKGDTTTSFLLIKSARPSDSGHYQCNPSNAKPKSVTVHVLNGVSHSVS-------RGVPSSNAA 482

Human   261 QVTQAPGGW-EVLAVVVPVPPFTCLLRDL------------VPATNYSLRVRCANALGPSPYADW 312
            :.|.|.... ..|:|.|||    |:|..|            ..||...|| ....|.|..|    
  Fly   483 RGTSASSPLAHSLSVCVPV----CVLLQLGACRWIAALLGAALATPPPLR-STRRATGERP---- 538

Human   313 VPFQTKGLAPASAPQNLHAIRTDSGLILEWE 343
               .:.|.||.:.... |.:.:    :|.|:
  Fly   539 ---GSPGCAPIACDMR-HFLAS----VLRWQ 561

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TYRO3NP_006284.2 IG_like 49..135 CDD:214653 23/101 (23%)
IGc2 56..121 CDD:197706 19/79 (24%)
Ig2_Tyro3_like 141..220 CDD:143226 20/91 (22%)
IG_like 145..220 CDD:214653 18/87 (21%)
FN3 225..317 CDD:238020 27/106 (25%)
fn3 324..406 CDD:278470 3/20 (15%)
PTKc_Tyro3 508..791 CDD:270659
Pkinase_Tyr 518..786 CDD:285015
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 815..837
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 851..871
dpr9NP_001287332.1 Ig 263..361 CDD:299845 24/108 (22%)
IG_like 263..360 CDD:214653 23/100 (23%)
IG_like 371..464 CDD:214653 24/96 (25%)
IGc2 377..456 CDD:197706 18/82 (22%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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