Sequence 1: | NP_001372133.1 | Gene: | TYK2 / 7297 | HGNCID: | 12440 | Length: | 1257 | Species: | Homo sapiens |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_015172.1 | Gene: | RAD53 / 855950 | SGDID: | S000006074 | Length: | 821 | Species: | Saccharomyces cerevisiae |
Alignment Length: | 306 | Identity: | 83/306 - (27%) |
---|---|---|---|
Similarity: | 137/306 - (44%) | Gaps: | 47/306 - (15%) |
- Green bases have known domain annotations that are detailed below.
Human 917 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKV 981
Human 982 SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQL 1046
Human 1047 VMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDR--LVK 1108
Human 1109 IGDFGLAKAVPEGHEYYRVREDGD------SPVFWYAPECLK-----------EYKFYYAS--DV 1154
Human 1155 WSFGVTLYELLT-HCDSSQSPPTKFLELIG---IAQGQMTVLRLTE 1196 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
TYK2 | NP_001372133.1 | FERM_F1 | 28..125 | CDD:408179 | |
FERM_F2 | 143..266 | CDD:408177 | |||
Jak1_Phl | 285..432 | CDD:407742 | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 335..366 | ||||
SH2 | 437..534 | CDD:417686 | |||
PKc_like | 589..937 | CDD:419665 | 6/19 (32%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 610..629 | ||||
PTKc_Tyk2_rpt2 | 962..1244 | CDD:270664 | 74/261 (28%) | ||
RAD53 | NP_015172.1 | FHA | 63..134 | CDD:238017 | |
STKc_Rad53_Cds1 | 196..465 | CDD:271000 | 73/258 (28%) | ||
FHA | 578..684 | CDD:238017 | |||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 0 | 0.000 | Not matched by this tool. | |||
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
1 | 0.910 |