Protein Alignment TWIST1 and Fer3

DIOPT Version :10

• Sequence 1: NP_000465.1
• Gene: TWIST1 / 7291
• HGNCID: 12428
• Length: 202
• Species: Homo sapiens
• Sequence 2: NP_524322.1
• Gene: Fer3 / 41411
• FlyBaseID: FBgn0037937
• Length: 195
• Species: Drosophila melanogaster
• Alignment Length: 84
• Identity: 35/84 - (41%)
• Similarity: 49/84 - (58%)
• Gaps: 1/84 - (1%)

Human    88 GGGGGSSSGGGSPQSYEELQTQRVMANVRERQRTQSLNEAFAALRKIIPTLPSDK-LSKIQTLKL 151
            |...||||.....:.......||..||:|||:|..:|||||..||:.:||...:| ||:|:||:|
  Fly    66 GRANGSSSSSKKTRRRVASMAQRRAANIRERRRMFNLNEAFDKLRRKVPTFAYEKRLSRIETLRL 130

Human   152 AARYIDFLYQVLQSDELDS 170
            |..||.|:.::|.....:|
  Fly   131 AITYIGFMAELLSGTPSNS 149

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TWIST1	NP_000465.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..105		5/16 (31%)
		bHLH_TS_TWIST1	98..174	CDD:381418	30/74 (41%)
		Sufficient for transactivation activity. /evidence=ECO:0000250	161..191		2/10 (20%)
Fer3	NP_524322.1	bHLH_TS_FERD3L_NATO3	79..142	CDD:381421	28/62 (45%)