Protein Alignment TWIST1 and HLH54F

DIOPT Version :9

• Sequence 1: NP_000465.1
• Gene: TWIST1 / 7291
• HGNCID: 12428
• Length: 202
• Species: Homo sapiens
• Sequence 2: NP_477302.1
• Gene: HLH54F / 37027
• FlyBaseID: FBgn0022740
• Length: 242
• Species: Drosophila melanogaster
• Alignment Length: 97
• Identity: 32/97 - (32%)
• Similarity: 50/97 - (51%)
• Gaps: 8/97 - (8%)

Human    93 SSSGGGSPQSYEELQTQRVMANVRERQRTQSLNEAFAALRKIIPTLPSD-KLSKIQTLKLAARYI 156
            :||....|      ..||..||.|||.|.:.|:.|:..|:..:|.:|.| ||||:.||:||..||
  Fly    22 ASSQSSQP------PVQRNAANARERMRMRVLSSAYGRLKTKLPNIPPDTKLSKLDTLRLATLYI 80

Human   157 DFLYQVLQSDELDSKMASCSYVAHERLSYAFS 188
            ..|...:::.. .|:....::..|..|:::.|
  Fly    81 KQLITAVETGS-HSQNHPHNHNQHHSLNHSHS 111

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TWIST1	NP_000465.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..105		3/11 (27%)
		HLH	109..159	CDD:278439	24/50 (48%)
		Sufficient for transactivation activity. /evidence=ECO:0000250	161..191		4/28 (14%)
HLH54F	NP_477302.1	HLH	32..83	CDD:278439	24/50 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149612
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840