Protein Alignment ZBTB8B and zbtb8b

DIOPT Version :10

• Sequence 1: NP_001139192.1
• Gene: ZBTB8B / 728116
• HGNCID: 37057
• Length: 495
• Species: Homo sapiens
• Sequence 2: XP_073786902.1
• Gene: zbtb8b / 550243
• ZFINID: ZDB-GENE-050417-42
• Length: 519
• Species: Danio rerio
• Alignment Length: 529
• Identity: 252/529 - (47%)
• Similarity: 330/529 - (62%)
• Gaps: 68/529 - (12%)

Human     1 MEMQSYYAKLLGELNEQRKRDFFCDCSIIVEGRIFKAHRNILFANSGYFRALLIHYIQDSG-RHS 64
            |::.||.::||.||||||||:||||||||||||:||||||||||:||||||||:||:||:| |||
Zfish    23 MDVPSYLSRLLSELNEQRKRNFFCDCSIIVEGRVFKAHRNILFASSGYFRALLVHYLQDNGQRHS 87

Human    65 TASLDIVTSDAFSIILDFLYSGKLDLCGENVIEVMSAASYLQMNDVVNFCKTYIRSSLDIC-RKM 128
            ||||||||::|||.||||||||:|||..:||||:|||||||||.|||||||.||:|||:|| |::
Zfish    88 TASLDIVTAEAFSFILDFLYSGRLDLRSDNVIEIMSAASYLQMTDVVNFCKGYIKSSLEICNREI 152

Human   129 EK--------EAAVAAAVAAAAAAAAAAAAAAAHQV-DSESPSSGREGTSCGTKSLVSSPAEGEK 184
            |:        .:|...:|.....|:.:.|.....|| ::.||........|...:..|..:|.|.
Zfish   153 ERLRERDGLDNSATPVSVTCTPVASTSEADQRTCQVTEALSPDDAPTAAVCTPANTSSKDSESEN 217

Human   185 SVECLRESPCGDCGDCHPLELVVRDSLGGGSADSNLSTPP---KRIEPKVEFDADEVEVDVGEQL 246
            |.        |...:..|:...::.|.|....:|  |||.   ..:.||:|:|.||    .||..
Zfish   218 SQ--------GAFPNHTPINAPLKVSPGPDLVNS--STPGLLLGLVHPKIEYDPDE----EGESS 268

Human   247 QQ------YAAP-------LNLAHVEEALPSGQAVDLAYSNYHVKQFLEALLRNSAAPSKDDADH 298
            ::      |..|       :|.:    ..||.:...::::|..:|||.:.|.|....|::|:
Zfish   269 RESKDAALYQGPNHDGERTVNTS----PAPSTEHSSVSFANCPMKQFPDVLYRGGMNPNRDE--- 326

Human   299 HFSRSL---EGRPEG---AGVAMSSMMDVQADWYGEDSGDVLVVPIKLHKCPFCPYTAKQKGILK 357
            |||::|   .|...|   .|.|....|:||.|||.:|.|       :||||||||||||||||||
Zfish   327 HFSQNLGYVSGFSRGDEVLGPAGPCGMEVQNDWYADDPG-------RLHKCPFCPYTAKQKGILK 384

Human   358 RHIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSNRPIICKGCRRTFTSHLSQGLRRFGLCD 422
            ||||.||||||||||.||||||||||||:||:|||||..||:|||||:.|:..:|.|::||||||
Zfish   385 RHIRCHTGERPYPCEVCGKRFTRQEHLRTHAISVHRSTWPIVCKGCRQVFSGIVSHGMKRFGLCD 449

Human   423 SCTCVTDTPDDDDDLMPINLSLVEASSESQEKSDTDNDWPIYVESGEENDPAGD--DSDDKPQIQ 485
            .||.||.|.:.|...|.:|:     ..|:.|:|..|:|||:::|.|:|.:.:..  :.|||..:.
Zfish   450 GCTFVTTTHNHDPSSMSLNI-----QPEAVERSARDSDWPMFMEEGDEAEASASNVEQDDKQIVV 509

Human   486 PNLSDRETL 494
            ..|:|..||
Zfish   510 KQLADNGTL 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZBTB8B	NP_001139192.1	BTB_POZ_ZBTB8B	6..118	CDD:349639	91/112 (81%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	157..178		3/20 (15%)
		zf-H2C2_5	341..365	CDD:404746	22/23 (96%)
		C2H2 Zn finger	343..363	CDD:275368	19/19 (100%)
		zf-H2C2_2	356..380	CDD:463886	21/23 (91%)
		C2H2 Zn finger	371..392	CDD:275368	17/20 (85%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	446..495		17/51 (33%)
zbtb8b	XP_073786902.1	None