Protein Alignment ZBTB8B and unc-98

DIOPT Version :10

• Sequence 1: NP_001139192.1
• Gene: ZBTB8B / 728116
• HGNCID: 37057
• Length: 495
• Species: Homo sapiens
• Sequence 2: NP_509284.2
• Gene: unc-98 / 181020
• WormBaseID: WBGene00006827
• Length: 310
• Species: Caenorhabditis elegans
• Alignment Length: 224
• Identity: 60/224 - (26%)
• Similarity: 80/224 - (35%)
• Gaps: 64/224 - (28%)

Human   281 LEALLRNSAA--PSK------DDADHHFSRSLEGRPEGAGVAMSSMMDVQADWYGEDSGDVLVVP 337
            :||.:.:|:|  |:|      |.:|..     |.|.:|.        .||.|    |:|.|
 Worm    68 VEAYVGSSSAQTPTKSSGGALDGSDQQ-----EVRQDGT--------SVQKD----DNGFV---- 111

Human   338 IKLHKCPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSNRPIICKG 402
              .:||.||..|......|:.|.|.|...:||.|..||..|.....|..|| :.|.......|:
 Worm   112 --FYKCRFCGLTFNFMNTLRAHERIHDVSQPYVCGKCGDSFEFACQLEYHA-AQHSEIDGYKCE- 172

Human   403 CRRTFTSHLSQGLRRFGLCDSCTCVTDTPDDDDDLMPINLSLVEASSESQEK---------SDTD 458
            |.|||.|:......:.         ||.|          |.|:.|...:..|         |:.|
 Worm   173 CGRTFFSYTEMLYHKH---------TDDP----------LELIGAPETTTIKVSKKRVLPVSEQD 218

Human   459 NDWPIYVESG-EENDP--AGDDSDDKPQI 484
            ...|.:|..| |...|  ..:|...||.|
 Worm   219 LPQPAFVTEGYEPKHPLRVYNDVRSKPYI 247

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZBTB8B	NP_001139192.1	BTB_POZ_ZBTB8B	6..118	CDD:349639
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	157..178
		zf-H2C2_5	341..365	CDD:404746	9/23 (39%)
		C2H2 Zn finger	343..363	CDD:275368	7/19 (37%)
		zf-H2C2_2	356..380	CDD:463886	10/23 (43%)
		C2H2 Zn finger	371..392	CDD:275368	7/20 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	446..495		13/51 (25%)
unc-98	NP_509284.2	C2H2 Zn finger	115..135	CDD:275368	7/19 (37%)
		C2H2 Zn finger	143..163	CDD:275368	7/20 (35%)
		SFP1	<169..268	CDD:227516	24/99 (24%)
		C2H2 Zn finger	171..189	CDD:275368	6/27 (22%)
		C2H2 Zn finger	248..268	CDD:275368	60/224 (27%)