Protein Alignment ZBTB8B and Y56A3A.28

DIOPT Version :10

• Sequence 1: NP_001139192.1
• Gene: ZBTB8B / 728116
• HGNCID: 37057
• Length: 495
• Species: Homo sapiens
• Sequence 2: NP_001366955.1
• Gene: Y56A3A.28 / 176632
• WormBaseID: WBGene00013240
• Length: 386
• Species: Caenorhabditis elegans
• Alignment Length: 441
• Identity: 92/441 - (20%)
• Similarity: 147/441 - (33%)
• Gaps: 150/441 - (34%)

Human   114 CKTYIRSSLD--------ICRKMEKEAAVAAAVAAAAAAAAAAAAAAAHQVDSESPSSGREGTSC 170
            |:.|.|:..:        :....|:|      ||.:.:..|....|...:...:.||....|...
 Worm    24 CRKYFRNKREFYWHTEDCLMEAFERE------VALSVSRGADEDIAENEEEWDDQPSEEALGLIA 82

Human   171 GTKSLVSSPAEGEKSVECLRESPCGDCGDCHPLELVVRDSLGGGSADSNLSTPPKRIEPKVE--F 233
            ..:   :||::.::.....:.||      ..|.:....:.:..|...|.:..   .:||:||  |
 Worm    83 KNE---ASPSKQQQPPPPPKSSP------RKPEKAQKEEKVIAGPRGSQIIV---SVEPQVEAGF 135

Human   234 DADEVEVDVGEQLQQYAAPLNLAHVEEALPSGQAVDLAYSNYHVKQFLEALLRNSAAPSKDDADH 298
            .:|:.:        ....||.::.||:........|:.                    :.||.:.
 Worm   136 QSDDDD--------DSEPPLLVSQVEQEKEDINEEDIG--------------------NNDDEEE 172

Human   299 HFSRSLEGRPEGAGVAMSSMMDVQADWYGED--------SGDVLVVPIKLH-------KCPFCPY 348
            .....||                    ||::        ||.|:..|....       :||.|..
 Worm   173 EMEGDLE--------------------YGDEETPLSFIPSGTVVGAPANQDDGSKPKMECPTCGL 217

Human   349 TAKQKGILKR-----HIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSNRPIICKGC-RRTF 407
                  :|.|     |.|.||||:||.|:.|||||.....|:.|. ..|...:|.:|..| .||.
 Worm   218 ------VLYRHNFAAHFRIHTGEQPYGCDYCGKRFRTTSSLKVHK-RAHTGEKPYVCPSCDYRTI 275

Human   408 TS----------HLSQG------LRRFGLCDSCTCVTDTPDDDDDLMPINLSL----------VE 446
            |.          |:...      :||     |.|.....|:|..:.:|..:..          |.
 Worm   276 TKRNLDRHIVNHHIRNAVIKGPIMRR-----SRTIPRYHPEDQVESIPTTMKYTVNEKSVRVSVA 335

Human   447 ASSESQEKSD----------TDNDWPIYVESGE---ENDPAGDDSDDKPQI 484
            |:...|.:.|          |.|: | |||..|   |..|.||:.|::.::
 Worm   336 ATRRRQLREDHTYISAAAASTSNE-P-YVEEEEEIIEEAPIGDEDDEEEEV 384

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZBTB8B	NP_001139192.1	BTB_POZ_ZBTB8B	6..118	CDD:349639	1/3 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	157..178		3/20 (15%)
		zf-H2C2_5	341..365	CDD:404746	8/35 (23%)
		C2H2 Zn finger	343..363	CDD:275368	7/24 (29%)
		zf-H2C2_2	356..380	CDD:463886	16/28 (57%)
		C2H2 Zn finger	371..392	CDD:275368	8/20 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	446..495		15/52 (29%)
Y56A3A.28	NP_001366955.1	C2H2 Zn finger	212..231	CDD:275368	7/24 (29%)
		zf-H2C2_2	223..248	CDD:463886	14/24 (58%)
		C2H2 Zn finger	239..259	CDD:275368	8/20 (40%)
		zf-H2C2_2	251..276	CDD:463886	8/25 (32%)
		C2H2 Zn finger	267..287	CDD:275368	5/19 (26%)