Protein Alignment ZBTB8B and ztf-6

DIOPT Version :10

• Sequence 1: NP_001139192.1
• Gene: ZBTB8B / 728116
• HGNCID: 37057
• Length: 495
• Species: Homo sapiens
• Sequence 2: NP_492877.1
• Gene: ztf-6 / 173014
• WormBaseID: WBGene00012317
• Length: 480
• Species: Caenorhabditis elegans
• Alignment Length: 475
• Identity: 97/475 - (20%)
• Similarity: 174/475 - (36%)
• Gaps: 111/475 - (23%)

Human    56 YIQDSGRHSTASLDIVTSDAFSIILDFL-YSGKLDLCGENVIEVMSAASYLQMNDVVN---FCKT 116
            |:|:.          ..|::.::|...: .:|.|:.|.|         |...||||:|   .|.|
 Worm    35 YVQEQ----------TPSNSTTVICTLVKITGALERCIE---------SNKAMNDVLNGKMKCTT 80

Human   117 YIRSSLDICRKMEKEAAVAAAVAAAAAA-----AAAAAAAAAHQVDSESPSSGREGTSC-GTKSL 175
            ...:|:.:.......|.......:..::     ...:||...|. |.|...|..|..|. ...|.
 Worm    81 CGATSVGLLSDCHDSATSTTTTVSHRSSEEPPRRKPSAAGGDHD-DEELECSSIESRSIRSVSSS 144

Human   176 VSSPAEGEKSVECLRESPCGDCGDCHPLELVVRDSLGGGSADSNLSTPPKRIEPKVEFDADEV-- 238
            |.:.||.:::.:.:....  |..|      |:...:.|.:..||.:|......|:.|.:..::
 Worm   145 VHTSAEDDETNQTMMVPT--DVAD------VINAIVAGTNGSSNSNTTSSSKSPQEEEEEHDLVM 201

Human   239 -------------EVDVGEQLQQYAAPL-NLAHVEEALPS---GQAVDLA----------YSNYH 276
                         ::::.|:|:.   || :.|.:::.|.:   ||...:.          ..|..
 Worm   202 KSILSTTTSTSNTKLELSEKLEN---PLQDTALLDQFLQASLLGQTPTVTPASEENEEDKEQNAV 263

Human   277 VKQFLEALLRNSAA------PSKDDADHHFSRSLEGRPEGAGVAMSSMMDVQADWYGEDSGDVL- 334
            :..||:.|..|..|      ....:.|...|.|....|.....::.|:...::......:|:||
 Worm   264 LTSFLQILFANQQAGNAILDAGSSENDGSTSSSQPSPPADPTASLDSLAMFESLLAESMNGNVLD 328

Human   335 ----------------VVPIKLHK--------CPF--CPYTAKQKGILKRHIRSHTGERPYPCET 373
                            ..|:|:.|        ||.  |....|:||.:.||..:|.|.| :.|:.
 Worm   329 ANTSSADQKAAARKRKSTPMKVPKSENGAGYICPMDGCNKVFKEKGSVHRHFVTHIGMR-FNCDK 392

Human   374 CGKRFTRQEHLRSHALSVHRSNRPIICKGCRRTFTSHLSQGLRRFGLCD-SCTCVTDTPDDDDDL 437
            |...:|::..|..|. .:|.:.....|:||...:|:  ..|||.....: :|..|::..:.:..|
 Worm   393 CKASYTQKHALMLHQ-KIHANPDAYQCRGCGTNYTT--QNGLRLHRQRNPACMEVSNALEFNTSL 454

Human   438 MPINLSLVEASSESQEKSDT 457
               |.|:.||.|....|:.:
 Worm   455 ---NTSISEALSGPLSKNSS 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZBTB8B	NP_001139192.1	BTB_POZ_ZBTB8B	6..118	CDD:349639	16/65 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	157..178		7/21 (33%)
		zf-H2C2_5	341..365	CDD:404746	10/33 (30%)
		C2H2 Zn finger	343..363	CDD:275368	8/21 (38%)
		zf-H2C2_2	356..380	CDD:463886	7/23 (30%)
		C2H2 Zn finger	371..392	CDD:275368	5/20 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	446..495		4/12 (33%)
ztf-6	NP_492877.1	SFP1	<346..435	CDD:227516	27/92 (29%)
		C2H2 Zn finger	361..383	CDD:275368	8/21 (38%)
		C2H2 Zn finger	390..410	CDD:275368	5/20 (25%)
		C2H2 Zn finger	418..435	CDD:275368	7/18 (39%)