Protein Alignment TUBB2A and betaTub97EF

DIOPT Version :10

• Sequence 1: NP_001060.1
• Gene: TUBB2A / 7280
• HGNCID: 12412
• Length: 445
• Species: Homo sapiens
• Sequence 2: NP_651606.2
• Gene: betaTub97EF / 43359
• FlyBaseID: FBgn0003890
• Length: 457
• Species: Drosophila melanogaster
• Alignment Length: 444
• Identity: 378/444 - (85%)
• Similarity: 417/444 - (93%)
• Gaps: 0/444 - (0%)

Human     1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEAAGNKYVPRAIL 65
            ||||||:||||||||||:||||:|||||||||.|.|||:|.||.|||:||||||:..||||||:|
  Fly     1 MREIVHLQAGQCGNQIGSKFWEIISDEHGIDPNGYYHGESALQHERIDVYYNEASSGKYVPRAVL 65

Human    66 VDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCL 130
            :|||||||||||..|.||:|||||||:||||||||||||||||||||:||||:|:|||||.||||
  Fly    66 IDLEPGTMDSVRQSPVGQLFRPDNFVYGQSGAGNNWAKGHYTEGAELIDSVLEVLRKESEGCDCL 130

Human   131 QGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVEN 195
            |||||.||||||||||:||||||||||||||||||:|||:||||||:.||||||||||:|||:.:
  Fly   131 QGFQLAHSLGGGTGSGLGTLLISKIREEYPDRIMNSFSVVPSPKVSEVVVEPYNATLSLHQLIVD 195

Human   196 TDETYSIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPF 260
            ||||:.||||||||||:::|::.:|||.|||||||.|||||||||||||||||||||||||||||
  Fly   196 TDETFCIDNEALYDICYQSLRICSPTYQDLNHLVSVTMSGVTTCLRFPGQLNADLRKLAVNMVPF 260

Human   261 PRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKE 325
            ||||||||||||||::||||||||||.||||||||:||||.|||||||||||||.||||.|||||
  Fly   261 PRLHFFMPGFAPLTAKGSQQYRALTVAELTQQMFDAKNMMTACDPRHGRYLTVACIFRGPMSMKE 325

Human   326 VDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFR 390
            ||.||.|||:|||||||||||||||.|||||||||||||||||||||||||:|||||||||||||
  Fly   326 VDTQMYNVQSKNSSYFVEWIPNNVKVAVCDIPPRGLKMSATFIGNSTAIQEIFKRISEQFTAMFR 390

Human   391 RKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATADEQGEFEEEEGEDE 444
            ||||||||||||||||||||||||||||:|||||||:||||::.||::|:.|.|
  Fly   391 RKAFLHWYTGEGMDEMEFTEAESNMNDLISEYQQYQEATADDEVEFDDEQAEQE 444

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TUBB2A	NP_001060.1	PLN00220	1..430	CDD:215107	370/428 (86%)
		MREI motif. /evidence=ECO:0000250|UniProtKB:P07437	1..4		2/2 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	422..445		14/23 (61%)
betaTub97EF	NP_651606.2	PLN00220	1..444	CDD:215107	377/442 (85%)