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Protein Alignment TUBB2A and CG7794

DIOPT Version :10

Sequence 1:	NP_001060.1	Gene:	TUBB2A / 7280	HGNCID:	12412	Length:	445	Species:	Homo sapiens
Sequence 2:	NP_650674.1	Gene:	CG7794 / 42159	FlyBaseID:	FBgn0038565	Length:	455	Species:	Drosophila melanogaster

Alignment Length:	452	Identity:	149/452 - (32%)
Similarity:	254/452 - (56%)	Gaps:	20/452 - (4%)

- Green bases have known domain annotations that are detailed below.

Human     3 EIVHIQAGQCGNQIGAKFWEVISDEHGIDPTG----SYHGDSDLQLERINVYYNEAAGNKYV-PR 62
            ||:.|..||.|.||....||:...||||...|    |...||.|      .::...:....| ||
  Fly     6 EIIQIHIGQAGVQIANACWELFCLEHGILANGRLTQSPMDDSFL------TFFEFTSHQPCVQPR 64

Human    63 AILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESC 127
            .:::|.||..:|.:|:|.:..:|.||..:.|:..:|:|:|:|:....:||:|..::.:|:.::.|
  Fly    65 LVMIDTEPTVIDEIRTGSYRNLFHPDTLITGKDDSGSNFARGYNLMASELLDRSMNAIRRVADRC 129

Human   128 DCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRI-MNTFSVMPSPKVSDTVVEPYNATLSVHQ 191
            ..|:||.:..::|||:|||:||.::.::.|::..:: :..|.|.|||.:|..:||||||.|:.|.
  Fly   130 RNLRGFLVFRAIGGGSGSGLGTRIMERLVEDFGKKMTVVEFLVYPSPSISPVIVEPYNALLAAHF 194

Human   192 LVENTDETYSIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVN 256
            .::..|.::.:|||||||||..||.:..|||.:||.:::..:|..|...||.|......::|..|
  Fly   195 SMDCADVSFIVDNEALYDICANTLNVPAPTYTNLNRIIAQVVSSFTASQRFGGGSTVSFQELQTN 259

Human   257 MVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRM 321
            :||:||:|:.:..:|||......|:..::..:||.|.|...|.|..|:|.||:|:....::||.:
  Fly   260 LVPYPRIHYPLINYAPLVPISHSQFVNMSTAQLTGQCFQMSNQMVRCNPSHGKYMASVLLYRGDI 324

Human   322 SMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPP---RGLKMSAT-----FIGNSTAIQELF 378
            :..|::..:.|::...|..||:|.|...|..|..:||   .|..::.|     .|.|:|.|:..:
  Fly   325 APNEINTALENIKRNRSFRFVDWSPTGFKIGVSPMPPYYVPGGDLAPTNRACVAISNNTNIRIAW 389

Human   379 KRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATADEQGEFEEEE 440
            .|:..:|..:::|:||::.|.|||::|..|.||..|:..||.:|.:...:....:.:.:.||
  Fly   390 CRLVNKFDKLYQRRAFVYHYVGEGLEEGNFNEASENICQLVHDYLEVDASAPTSRRDSDPEE 451

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.