Protein Alignment TUBB2A and betaTub85D

DIOPT Version :10

• Sequence 1: NP_001060.1
• Gene: TUBB2A / 7280
• HGNCID: 12412
• Length: 445
• Species: Homo sapiens
• Sequence 2: NP_524290.2
• Gene: betaTub85D / 41124
• FlyBaseID: FBgn0003889
• Length: 446
• Species: Drosophila melanogaster
• Alignment Length: 446
• Identity: 423/446 - (94%)
• Similarity: 434/446 - (97%)
• Gaps: 2/446 - (0%)

Human     1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEAAGNKYVPRAIL 65
            |||||||||||||||||.||||||||||.||.||:|:|||||||||||||||||.|.||||||||
  Fly     1 MREIVHIQAGQCGNQIGGKFWEVISDEHCIDATGTYYGDSDLQLERINVYYNEATGAKYVPRAIL 65

Human    66 VDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCL 130
            ||||||||||||||.|||||||||||||||||||||||||||||||||||||||||||||.||||
  Fly    66 VDLEPGTMDSVRSGAFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESEGCDCL 130

Human   131 QGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVEN 195
            |||||||||||||||||||||||||||||||||||||||:|||||||||||||||||||||||||
  Fly   131 QGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVEN 195

Human   196 TDETYSIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPF 260
            |||||.|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Fly   196 TDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPF 260

Human   261 PRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKE 325
            |||||||||||||||||||||||||||||||||||:|||||||||||||||||||||||||||||
  Fly   261 PRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAIFRGRMSMKE 325

Human   326 VDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFR 390
            |||||||:||||||:||||||||.|||||||||||||||||||||||||||||||:|||||||||
  Fly   326 VDEQMLNIQNKNSSFFVEWIPNNCKTAVCDIPPRGLKMSATFIGNSTAIQELFKRVSEQFTAMFR 390

Human   391 RKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATADEQGEFEEEE--GEDE 444
            ||||||||||||||||||||||||||||||||||||:|||||:|||:|:|  |.||
  Fly   391 RKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQEATADEEGEFDEDEEGGGDE 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TUBB2A	NP_001060.1	PLN00220	1..430	CDD:215107	411/428 (96%)
		MREI motif. /evidence=ECO:0000250|UniProtKB:P07437	1..4		2/2 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	422..445		18/25 (72%)
betaTub85D	NP_524290.2	PLN00220	1..430	CDD:215107	411/428 (96%)