Protein Alignment GOLGA6L6 and NST1

DIOPT Version :9

• Sequence 1: NP_001138476.2
• Gene: GOLGA6L6 / 727832
• HGNCID: 37225
• Length: 724
• Species: Homo sapiens
• Sequence 2: NP_014308.1
• Gene: NST1 / 855633
• SGDID: S000005035
• Length: 1240
• Species: Saccharomyces cerevisiae
• Alignment Length: 722
• Identity: 154/722 - (21%)
• Similarity: 288/722 - (39%)
• Gaps: 159/722 - (22%)

Human    41 KETRQSKLAEAKEQ----------LTDHHPQTNPSVGTAASDTKKKKINNG-TNPETTTSGGCHS 94
            |:.|.:.|...|:.          |..|....:|.........:|:::.|. .|.:...|..|..
Yeast    75 KKERTANLTHNKDSMDSASSLAFTLDSHWESLSPEEKKTILRIEKEEVFNVIRNYQDDHSCSCSV 139

Human    95 PEDEQKASHQHQE-------ALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGE-ARDL 151
            ......|..|..|       |:.::.:.:.:.|:.......|||::....|:.:...:|| .::.
Yeast   140 CGRRHLAMDQEMERIYNTLYAMDKDKDPETNPIKFHLGIIKELQISKNQQQNDLSSTKGEVVKNF 204

Human   152 ISR----------LHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEE 206
            :|.          ||...|...:.|||.:..|......:..:..:...:.:..:....|:::|||
Yeast   205 LSSSTVGSLKEEVLHFKQKQLSKQEQAHNETADNTSLLEENLNNIHINKTSSEISANFNSVSDEE 269

Human   207 LKEKNA---------------ELQEKL-------------------------------------- 218
            |::|.:               |..:|:
Yeast   270 LQQKYSNFTKTFISSHPKIAEEYVQKMMMYPNIRALTDDLMNSNGQGFLNAIEDFVRDGQIQASK 334

Human   219 ---QLVESEKSEIQL-NVKELKRKLERAKLLLPQQQLQAE---ADHLGKELQSVSAKLQ--AQVE 274
               .:.|.|.|...| :.||....|...|.|...:....:   |:.:.....:.|.|.:  :|:|
Yeast   335 KDDSITEDEASSTDLTDPKEFTTMLHSGKPLTEDEYADLQRNIAERMTNAYDTASKKFKDVSQLE 399

Human   275 ENELWNRLNQQQEEKMWRQEEKIQEWEEKI-------------------QEQEEKI-------RE 313
            : ||:.|....:::|.:| |..||.::.|.                   |.::..:       .|
Yeast   400 K-ELFTRFMSGRDKKSFR-ELIIQSFKNKFDGELGPSVLAATLSSCFSSQSKDTSLDTDSIYEDE 462

Human   314 QEEKIREQEEKMRRQEEMM-WEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQ 377
            .||...:..|.....||:. :|..|.:.:.|..  ||...:|....:.::.:.| |:.....|..
Yeast   463 DEEDYDDYSEYAEDSEEVSEYEGIEAVEKPEHD--EKSNGIRETLHLSYDHDHK-RQNHPHHHYH 524

Human   378 EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHE---QEK 439
            ......|::..|||.|.:.|...:......|.::.:...|::..|:::.....||..::   .|.
Yeast   525 STSTHSEDELSEEEYISDIELPHDPHKHFHRDDDILDGDEDEPEEEDENEGDDEEDTYDSGLDET 589

Human   440 IREEEKRQ----------------EQEEMWRQEEKIREQEEIWRQKEKMHEQEEKIRKQEEKVWR 488
            .|.||.|:                ...|......:::..:|:..:|.|..|:|||.:|:.||
Yeast   590 DRLEEGRKLIQIAITKLLQSRIMASYHEKQADNNRLKLLQELEEEKRKKREKEEKKQKKREK--- 651

Human   489 QEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHE-QEKIWEEEKRQEQEDKMWRQEEK 552
              ||.:::.:::.::|||..|:|||.|.::|:...|.:..| |.|..||.||::.|::..|.||:
Yeast   652 --EKEKKRLQQLAKEEEKRKREEEKERLKKELEEREMRRREAQRKKVEEAKRKKDEERKRRLEEQ 714

Human   553 IREQEEKVWRQEEKIREQEE--KRQEQEEKMWKQEEKIREQEEKIREQEEKIREQ---EEKIREQ 612
            .|.:|     .:||.|:|:|  ||:.:|||...:|:|..|||:..:|:||:.|::   |:.:|:|
Yeast   715 QRREE-----MQEKQRKQKEELKRKREEEKKRIREQKRLEQEKLQKEKEEEERQRLIAEDALRKQ 774

Human   613 EEMTQEQ 619
             ::.:||
Yeast   775 -KLNEEQ 780

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GOLGA6L6	NP_001138476.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..108		15/84 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	314..342		7/28 (25%)
		TPH	367..713	CDD:290579	78/278 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	374..454		18/98 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	517..548		10/31 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	561..724		24/64 (38%)
NST1	NP_014308.1	NST1	<103..159	CDD:372833	9/55 (16%)
		ARGLU	<694..727	CDD:405931	14/37 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000