Protein Alignment TTR and ttr

DIOPT Version :10

• Sequence 1: NP_000362.1
• Gene: TTR / 7276
• HGNCID: 12405
• Length: 147
• Species: Homo sapiens
• Sequence 2: NP_001005598.2
• Gene: ttr / 449556
• ZFINID: ZDB-GENE-040927-14
• Length: 149
• Species: Danio rerio
• Alignment Length: 140
• Identity: 70/140 - (50%)
• Similarity: 97/140 - (69%)
• Gaps: 3/140 - (2%)

Human     6 LLLLCLAGLVFVSEAGPT---GTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASG 67
            ::.:.||.|..:..:.|.   |..::.|||.||:||||:|:||.|:|:.:||:....|||..|||
Zfish     5 VICVLLASLFALCRSAPVAFHGGSDAHCPLTVKILDAVKGTPAGNIALDLFRQDQGGTWEKIASG 69

Human    68 KTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLS 132
            |...:||:|.|.||:||..|:|:||.||.:|||..|.:|||:.|:|||.|:..|.|.||:|.|||
Zfish    70 KVDMTGEVHNLITEQEFTPGVYRVEFDTLTYWKTEGRTPFHQLADVVFEAHAEGHRHYTLALLLS 134

Human   133 PYSYSTTAVV 142
            |:||:|||||
Zfish   135 PFSYTTTAVV 144

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTR	NP_000362.1	TR_THY	27..147	CDD:128406	65/116 (56%)
ttr	NP_001005598.2	Peptidase_M14NE-CP-C_like	26..144	CDD:473874	64/117 (55%)