Protein Alignment TTR and ttr

DIOPT Version :10

• Sequence 1: NP_000362.1
• Gene: TTR / 7276
• HGNCID: 12405
• Length: 147
• Species: Homo sapiens
• Sequence 2: NP_001096539.1
• Gene: ttr / 100125183
• XenbaseID: XB-GENE-479395
• Length: 151
• Species: Xenopus tropicalis
• Alignment Length: 151
• Identity: 85/151 - (56%)
• Similarity: 109/151 - (72%)
• Gaps: 6/151 - (3%)

Human     1 MASHRLLLLCLAGLVFVSEAGP----TGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTW 61
            ||..:..|| ||.|...|||.|    .|..:|||||||||||||||.||.|:.|.|||. .:..|
 Frog     1 MAFFKSFLL-LALLAIASEAAPGHVSHGEADSKCPLMVKVLDAVRGIPAANLLVQVFRN-TEGNW 63

Human    62 EPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYT 126
            |..:||||:|.||:|.:.|:|:|.||:||:|..||::|:.||:|||||:.:|||:|||:|.|.||
 Frog    64 ELISSGKTTELGEIHNIITDEQFTEGVYKIEFATKTFWRKLGLSPFHEYVDVVFSANDAGHRHYT 128

Human   127 IAALLSPYSYSTTAVVTNPKE 147
            ||.||:|||.|:||||:.|.:
 Frog   129 IAVLLTPYSISSTAVVSEPHD 149

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTR	NP_000362.1	TR_THY	27..147	CDD:128406	73/119 (61%)
ttr	NP_001096539.1	Peptidase_M14NE-CP-C_like	27..146	CDD:473874	73/119 (61%)