DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment TSNAX and Trax

DIOPT Version :9

Sequence 1:	NP_005990.1	Gene:	TSNAX / 7257	HGNCID:	12380	Length:	290	Species:	Homo sapiens
Sequence 2:	NP_650454.2	Gene:	Trax / 41871	FlyBaseID:	FBgn0038327	Length:	298	Species:	Drosophila melanogaster

Alignment Length:	285	Identity:	104/285 - (36%)
Similarity:	161/285 - (56%)	Gaps:	26/285 - (9%)

- Green bases have known domain annotations that are detailed below.

Human     4 KEGSGGFRKRKHDNFPHNQRREGKDVNSSSPVMLAFKSFQQELDARHDKYERLVKLSRDITVESK 68
            |.|..|.|    :..|..::.....::..||::..|:.:..||..:||::||:||||||||:|||
  Fly     3 KNGGAGHR----NTAPRKRQIPAAQLDEDSPIVQQFRIYSNELIMKHDRHERIVKLSRDITIESK 63

Human    69 RTIFLLHRITS-APDMEDILTESEIKLDGVRQKIFQ-VAQELSGEDMHQFHRAITTGLQEYVEAV 131
            |.|||||.|.| ..:.|.:|.|:..:|:.:....|: ||.||..:|::||..:.:.||||::||.
  Fly    64 RIIFLLHSIDSRKQNKEKVLEEARQRLNKLIAVNFRAVALELRDQDVYQFRSSYSPGLQEFIEAY 128

Human   132 SFQHFI---------KTRSLISMDEINKQLIFTTEDN-GKENKTPSSDAQ-------DKQFGTWR 179
            ::..::         :|:|:.....|...:.:..|.: .||..|...|.|       .|:|   :
  Fly   129 TYMEYLCHEDAEGENETKSVSDWQAIQAVMQYVEESSQPKEEPTEGEDVQAIAQVESPKKF---Q 190

Human   180 LRVTPVDYLLGVADLTGELMRMCINSVGNGDIDTPFEVSQFLRQVYDGFSFIGNTGPYEVSKKLY 244
            ..|.|.:|:||::||||||||.||||:|:||.||..:..:.|:..|.|:..:......|:.:|:.
  Fly   191 FFVDPTEYILGLSDLTGELMRRCINSLGSGDTDTCLDTCKALQHFYSGYISLNCQRARELWRKIT 255

Human   245 TLKQSLAKVENACYALKVRGSEIPK 269
            |:|||:.|.||.||.:||||.|..|
  Fly   256 TMKQSVLKAENVCYNVKVRGGEAAK 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TSNAX	NP_005990.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..32		5/27 (19%)
		Translin-like	42..256	CDD:271348	87/232 (38%)
		Interaction with C1D. /evidence=ECO:0000269\|PubMed:11801738	73..208		51/153 (33%)
Trax	NP_650454.2	Translin-like	37..267	CDD:271348	87/232 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141393
Domainoid	1	1.000	151	1.000	Domainoid score	I4378
eggNOG	1	0.900	-	-		E1_COG2178
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4374
Inparanoid	1	1.050	171	1.000	Inparanoid score	I4102
Isobase	1	0.950	-	1.056642	Normalized mean entropy	S6820
OMA	1	1.010	-	-		QHG55787
OrthoDB	1	1.010	-	-		D1213910at2759
OrthoFinder	1	1.000	-	-		FOG0006191
OrthoInspector	1	1.000	-	-		oto88929
orthoMCL	1	0.900	-	-		OOG6_105072
Panther	1	1.100	-	-	LDO	PTHR10741
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1561
SonicParanoid	1	1.000	-	-		X4467
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	17	16.750