Protein Alignment TRPS1 and GATAe

DIOPT Version :9

• Sequence 1: NP_054831.2
• Gene: TRPS1 / 7227
• HGNCID: 12340
• Length: 1294
• Species: Homo sapiens
• Sequence 2: NP_650516.2
• Gene: GATAe / 41945
• FlyBaseID: FBgn0038391
• Length: 746
• Species: Drosophila melanogaster
• Alignment Length: 929
• Identity: 182/929 - (19%)
• Similarity: 295/929 - (31%)
• Gaps: 377/929 - (40%)

Human   433 LDSSRQNGTEATSYYWCKFCSFSCESSSSLKLLEHYGKQH--------GAV----QSGGLNPELN 485
            |:||  ||.:          ..:.:::::|...:...:||        |.|    |:|...||
  Fly    58 LESS--NGAD----------QLAQQTANNLDEQQEQQQQHQQQAATSVGVVVQTGQAGVSEPE-- 108

Human   486 DKLSRGSVINQN-----------DLAKSSEGETMTKTDKSSSGAKKKDFSSKGAEDNMVTSYNCQ 539
               .:..|:.:|           :|.::.|||..|....:|||:         |.|:.:
  Fly   109 ---EQYVVVPRNQRRILTTAGTLELNEAREGEPSTNASNASSGS---------ASDSHI------ 155

Human   540 FCDFRYSKSHGPDVIVVGPLLRHYQQLHNIHKCTIKHCPFCPRGLCSPEKHLGEIT--------- 595
              :::.|....|..       .||.|:             .||.        .|:|
  Fly   156 --EYQRSAHQSPGA-------THYVQM-------------APRN--------AEVTEQVGAAAGA 190

Human   596 -------YPFACRKSNCSHCALLLLHLSPG-AAGSSRVK---------HQCHQCSFTTPDVDVLL 643
                   ||..|...:.:  |:.:..|..| |.|.|:.:         .|..||  .||:
  Fly   191 PPGTIFAYPIICNGDDVA--AIKIETLEKGEATGESQQQQQQLQQHQHQQQQQC--PTPN----- 246

Human   644 FHYESVHESQASDVKQEANHLQGSDGQQSVKESKEHSCTKCDFITQVEEEISRHYRRAHSCYKCR 708
                .....:...:..||..||....||...:.::|                   ::.|..::..
  Fly   247 ----GASYGETIVISSEAEALQHHHQQQQQHQQQQH-------------------QQQHHQHQAA 288

Human   709 QCSFTAADTQSLL--EHFNTVHCQEQDI--TTANGEEDGHAISTIKEEPKIDFRV---------- 759
            ..:..||.|..:.  .|..||....:|:  |||..|..  |.:...:.|.:|..|
  Fly   289 AAASAAAQTVHIATSSHGGTVRFVTEDVRFTTAGPETS--ASNMYYDVPVVDGSVHANESKTYAD 351

Human   760 ----YNLLTPDS-----------KMGEPV------------SESVVKREKL-------------- 783
                |....|.|           :.|..:            |||.:.:..|
  Fly   352 LGNAYAPFPPSSSFSSNSYAATLQQGNTIYSVPGTGQFLAKSESGLNQTGLLRQTGPATFQTISF 416

Human   784 EEKDGLKEKVWTESSSDDLRNVTWR----------GADILRGSPSYTQASLGLLTPVSGTQEQTK 838
            |..:|: |.:|...:..:.::|.:.          |:..:..|.....:|:|..
  Fly   417 EGGNGI-EPLWASPAPPEYQSVQFSNFHPQVIDEYGSGNMSTSHWPPASSIGQY----------- 469

Human   839 TLRDSPNVEAAHLARPIYGLAVET-------KG---FLQGAPAGGEKSGALPQQYPASGENKSKD 893
               |...|.|:..:.|.:.|..|.       ||   |....|       |..:..|...:.::|.
  Fly   470 ---DGSLVTASSTSSPNHELKCENCHGPFLRKGSEYFCPNCP-------AFMRMAPRITQRQAKP 524

Human   894 ESQSLLRRRRGSGVFCANCLTTKTSLWRKNANGGYVCNACGLYQKLHSTPRPLNIIKQNNGEQII 958
            ::.:....|| :||.||||.|..|:|||:|..|..||||||||.|||:..|||::.|:.     |
  Fly   525 KAAAAPNNRR-NGVTCANCQTNSTTLWRRNNEGNPVCNACGLYYKLHNMNRPLSMKKEG-----I 583

Human   959 RRRTRKRLNPEALQAEQLNKQQRGSNEEQVNGSPLERRSEDHLTESHQREIPLPSLSKYEAQGSL 1023
            ::|.||..|.                    .|:|:.|             .||||:|    ||..
  Fly   584 QKRKRKPKNN--------------------GGAPMHR-------------APLPSMS----QGVN 611

Human  1024 TKSHSAQQPVLVSQTLDIHKRMQPLHIQIKSPQES---------TGDPGNSSSVSEGKGSSERGS 1079
            ..::|...|..|..::        |:.|:.|.|.|         ||..|....||....::...:
  Fly   612 LMANSPLYPSQVPVSM--------LNSQLNSQQNSSPELHDMSTTGQAGGQRVVSISLNATAPPT 668

Human  1080 PIEKYMRPAKHPNYSPPGSPIEKYQYPLFGLPFVHNDFQSEADWLRFWSKYKLSVPGNPHYLSHV 1144
            |.......|:|                                                    ||
  Fly   669 PDGTLNMSARH----------------------------------------------------HV 681

Human  1145 PGLPNPCQNYVPYPTFNLP----PHFSAVGSDNDIPLDLAIKHSRPGPTANGASKEKTKAPPNVK 1205
            .|     :::.||...:.|    ||....     :|::..|  .:|.||...:....|:..|:|
  Fly   682 TG-----ESHSPYSQQSTPQSQSPHLPGT-----VPINRQI--VQPVPTIESSRSSNTELTPSV- 733

Human  1206 NEGPLNVVKTEKVDRSTQD 1224
                  :.:|...:||:.:
  Fly   734 ------ITRTGLPERSSNN 746

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TRPS1	NP_054831.2	ZnF_GATA	904..947	CDD:214648	26/42 (62%)
		ZnF_GATA	908..964	CDD:238123	28/55 (51%)
GATAe	NP_650516.2	ZnF_GATA	534..583	CDD:214648	29/54 (54%)
		ZnF_GATA	538..589	CDD:238123	28/55 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5641
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810