powered by:
Protein Alignment TRPC5 and BSC1
DIOPT Version :10
| Sequence 1: | NP_036603.1 |
Gene: | TRPC5 / 7224 |
HGNCID: | 12337 |
Length: | 973 |
Species: | Homo sapiens |
| Sequence 2: | NP_010247.1 |
Gene: | BSC1 / 851524 |
SGDID: | S000002195 |
Length: | 328 |
Species: | Saccharomyces cerevisiae |
| Alignment Length: | 172 |
Identity: | 34/172 - (19%) |
| Similarity: | 58/172 - (33%) |
Gaps: | 17/172 - (9%) |
- Green bases have known domain annotations that are detailed below.
|
Human 783 NNDGSGGARAKSKSVSFNLGCKKKTCHGPPLIRTMPRSSGAQGKSKAESSSKRSFMGPSLKKLGL 847
||||:....:.|...:.::.....|........|...||.....:.:.|::..|....|......
Yeast 152 NNDGTCTKASSSSITTSSITTSSTTTSSTTTSSTTTSSSTTSSSTTSSSTTSSSTTSSSTTSSST 216
Human 848 LFSKFNGHMSEPSSEPMYTISDGIVQQHCMWQDIRYSQMEKGKAEACSQSEINL-------SEVE 905
..|......:..|| |.|.............:.|.......::.|.:.|:. :...
Yeast 217 TSSSTTSSSTTSSS----TTSSSTTSSSTTSSSTKTSTTTSSTVKSSSTTSIDFTTSVDSHTSSS 277
Human 906 LGEVQGAAQSSE-CPLACSSSLHCASSICSSNSKLLDSSEDV 946
:.::..:..|:: ..||.|:|.. ||..||:| .||.||
Yeast 278 VADIYRSRTSTDVTTLAASTSPF--SSFTSSDS---SSSSDV 314
|
Known Domains:
Indicated by green bases in alignment.
| Gene | Sequence | Domain | Region |
External ID | Identity |
| TRPC5 | NP_036603.1 |
trp |
17..756 |
CDD:273311 |
|
| ANK 1. /evidence=ECO:0000269|PubMed:37137991, ECO:0007744|PDB:7X6C, ECO:0007744|PDB:7X6I, ECO:0007744|PDB:8GVW, ECO:0007744|PDB:8GVX |
30..60 |
|
|
| ANK repeat |
35..67 |
CDD:293786 |
|
| ANK repeat |
69..98 |
CDD:293786 |
|
| ANK 2. /evidence=ECO:0000269|PubMed:37137991, ECO:0007744|PDB:7X6C, ECO:0007744|PDB:7X6I, ECO:0007744|PDB:8GVW, ECO:0007744|PDB:8GVX |
69..97 |
|
|
| ANK 3. /evidence=ECO:0000269|PubMed:37137991, ECO:0007744|PDB:7X6C, ECO:0007744|PDB:7X6I, ECO:0007744|PDB:8GVW, ECO:0007744|PDB:8GVX |
98..124 |
|
|
| ANK 4. /evidence=ECO:0000269|PubMed:37137991, ECO:0007744|PDB:7X6C, ECO:0007744|PDB:7X6I, ECO:0007744|PDB:8GVW, ECO:0007744|PDB:8GVX |
141..170 |
|
|
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite |
766..794 |
|
4/10 (40%) |
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite |
810..837 |
|
4/26 (15%) |
| Essential for binding to NHERF1 PDZ domain. /evidence=ECO:0000250|UniProtKB:Q9QX29 |
971..973 |
|
|
| BSC1 | NP_010247.1 |
Flo11 |
4..141 |
CDD:401990 |
|
|
Blue background indicates that the domain is not in
the aligned region.
|
Return to query results.
Submit another query.
