Protein Alignment TPM4 and tpm4

DIOPT Version :10

• Sequence 1: NP_001138632.1
• Gene: TPM4 / 7171
• HGNCID: 12013
• Length: 284
• Species: Homo sapiens
• Sequence 2: XP_012818712.1
• Gene: tpm4 / 549841
• XenbaseID: XB-GENE-6077097
• Length: 284
• Species: Xenopus tropicalis
• Alignment Length: 284
• Identity: 260/284 - (91%)
• Similarity: 272/284 - (95%)
• Gaps: 0/284 - (0%)

Human     1 MEAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKYSEDLK 65
            ||||||||||||||||||||||||||||||||||||||||:||..|||||||||||||||||.||
 Frog     1 MEAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEDELVALQKKLKGTEDELDKYSEALK 65

Human    66 DAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVI 130
            |||||||..:|||:||||:||||||||||||||||||||||||||||||||||||||||||||||
 Frog    66 DAQEKLEQADKKATDAEGEVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVI 130

Human   131 ENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEE 195
            |||||||||||||||:||||||||||||||||||||||||||||||||||||||||||||.||||
 Frog   131 ENRAMKDEEKMEIQELQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELKCSDLEE 195

Human   196 ELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKL 260
            ||||||||||||||.||||||||||||||||:|:|||||||||||||||:||||||||||||:||
 Frog   196 ELKNVTNNLKSLEAQSEKYSEKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKL 260

Human   261 AQAKEENVGLHQTLDQTLNELNCI 284
            |.|||||:|:||.|||||.||..:
 Frog   261 ATAKEENLGMHQVLDQTLQELGSL 284

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TPM4	NP_001138632.1	Tropomyosin	48..282	CDD:459736	215/233 (92%)
tpm4	XP_012818712.1	Tropomyosin	48..281	CDD:459736	214/232 (92%)