Protein Alignment TPM4 and Tpm4

DIOPT Version :10

• Sequence 1: NP_001138632.1
• Gene: TPM4 / 7171
• HGNCID: 12013
• Length: 284
• Species: Homo sapiens
• Sequence 2: NP_001001491.1
• Gene: Tpm4 / 326618
• MGIID: 2449202
• Length: 248
• Species: Mus musculus
• Alignment Length: 284
• Identity: 210/284 - (73%)
• Similarity: 227/284 - (79%)
• Gaps: 42/284 - (14%)

Human     1 MEAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKYSEDLK 65
            :||:|:|:|.|:...::|.|||:                     .||::|.|..:..:|
Mouse     7 LEAVKRKIQALQQQADDAEDRAQ---------------------GLQRELDGERERREK------ 44

Human    66 DAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVI 130
                           ||||.|||||||||:|||||||||:||||||.||||||||||||||||||
Mouse    45 ---------------AEGDAAALNRRIQLLEEELDRAQEQLATALQNLEEAEKAADESERGMKVI 94

Human   131 ENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEE 195
            |||||||||||||.||||||||||.:||||||||||||||||||||:||||||||||||||||||
Mouse    95 ENRAMKDEEKMEILEMQLKEAKHITDEADRKYEEVARKLVILEGELKRAEERAEVSELKCGDLEE 159

Human   196 ELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKL 260
            |||||||||||||||||||||||||||||||||||||||||||||||||||:|||||||||||||
Mouse   160 ELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVSKLEKTIDDLEEKL 224

Human   261 AQAKEENVGLHQTLDQTLNELNCI 284
            ||||||||||||||||||||||||
Mouse   225 AQAKEENVGLHQTLDQTLNELNCI 248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TPM4	NP_001138632.1	Tropomyosin	48..282	CDD:459736	194/233 (83%)
Tpm4	NP_001001491.1	Tropomyosin	12..246	CDD:459736	203/275 (74%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	18..49		12/72 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	78..97		18/18 (100%)