Protein Alignment TPM4 and cdc8

DIOPT Version :10

• Sequence 1: NP_001138632.1
• Gene: TPM4 / 7171
• HGNCID: 12013
• Length: 284
• Species: Homo sapiens
• Sequence 2: NP_594530.1
• Gene: cdc8 / 2541940
• PomBaseID: SPAC27F1.02C
• Length: 161
• Species: Schizosaccharomyces pombe
• Alignment Length: 167
• Identity: 44/167 - (26%)
• Similarity: 91/167 - (54%)
• Gaps: 8/167 - (4%)

Human     1 MEAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKYSEDLK 65
            |:.:::|:...:.:.:.|:.|||.|||..|..|.:....|:|...|.:|.:..|.:|::..|:.|
pombe     1 MDKLREKINAARAETDEAVARAEAAEAKLKEVELQLSLKEQEYESLSRKSEAAESQLEELEEETK 65

Human    66 DAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVI 130
            ..:.|.:..:.:.::||    .|:|:::|:||||:...:.|....:|:.:.:..|:..||.::.:
pombe    66 QLRLKADNEDIQKTEAE----QLSRKVELLEEELETNDKLLRETTEKMRQTDVKAEHFERRVQSL 126

Human   131 ENRAMKDEEKMEIQEMQLKEAKHIAE--EADRKYEEV 165
            |..  :|:.:.:::||..|..|..||  |..:..|::
pombe   127 ERE--RDDMEQKLEEMTDKYTKVKAELDEVHQALEDL 161

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TPM4	NP_001138632.1	Tropomyosin	48..282	CDD:459736	30/120 (25%)
cdc8	NP_594530.1	Tropomyosin_1	7..148	CDD:403808	39/146 (27%)