Protein Alignment TPM3 and Tm2

DIOPT Version :10

• Sequence 1: NP_689476.2
• Gene: TPM3 / 7170
• HGNCID: 12012
• Length: 285
• Species: Homo sapiens
• Sequence 2: NP_524361.4
• Gene: Tm2 / 41853
• FlyBaseID: FBgn0004117
• Length: 284
• Species: Drosophila melanogaster
• Alignment Length: 281
• Identity: 132/281 - (46%)
• Similarity: 196/281 - (69%)
• Gaps: 0/281 - (0%)

Human     2 MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALK 66
            |:|||||||.:||:|:||:|:|:..|.:.|.|..|:.:|.:|:..::||....|.:|....|.|:
  Fly     1 MDAIKKKMQAMKLEKDNAIDKADTCENQAKDANSRADKLNEEVRDLEKKFVQVEIDLVTAKEQLE 65

Human    67 DAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVI 131
            .|..:||..||.....|:|||:.||::|.:||:|::::||..||.|||.||.::|||:.|..||:
  Fly    66 KANTELEEKEKLLTATESEVATQNRKVQQIEEDLEKSEERSTTAQQKLLEATQSADENNRMCKVL 130

Human   132 ENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEE 196
            |||:.:|||:|:....|||||:.:||:||.|.:||:|||..:|.:||..|:|....|||..||||
  Fly   131 ENRSQQDEERMDQLTNQLKEARMLAEDADTKSDEVSRKLAFVEDELEVAEDRVRSGESKIMELEE 195

Human   197 ELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDEL 261
            |||.|.|:|||||...||.:|:.::::.|:|.|:.||||||.|||.||:.|.:|:|.:|.|||||
  Fly   196 ELKVVGNSLKSLEVSEEKANQRVEEFKREMKTLSIKLKEAEQRAEHAEKQVKRLQKEVDRLEDEL 260

Human   262 YAQKLKYKAISEELDHALNDM 282
            ...|.:||::::|:|....::
  Fly   261 GINKDRYKSLADEMDSTFAEL 281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TPM3	NP_689476.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	16..44		10/27 (37%)
		Tropomyosin	49..283	CDD:459736	111/234 (47%)
Tm2	NP_524361.4	Tropomyosin	48..281	CDD:459736	111/232 (48%)