Protein Alignment TPM2 and TPM2

DIOPT Version :10

• Sequence 1: XP_016870577.1
• Gene: TPM2 / 7169
• HGNCID: 12011
• Length: 303
• Species: Homo sapiens
• Sequence 2: NP_012128.3
• Gene: TPM2 / 854668
• SGDID: S000001400
• Length: 161
• Species: Saccharomyces cerevisiae
• Alignment Length: 164
• Identity: 41/164 - (25%)
• Similarity: 96/164 - (58%)
• Gaps: 4/164 - (2%)

Human    44 QALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLAT 108
            :.:::||...:.|.|.:.|..:|.:|:|::.|:..|:.|.::.||:.:.:.::.|:::.:.:|:.
Yeast     2 EKIKEKLNSLKLESESWQEKYEELREQLKELEQSNTEKENEIKSLSAKNEQLDSEVEKLESQLSD 66

Human   109 ALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILE 173
            ..|..|::......:|...|  :|:.:  |:::|..|.:||||....:::|...|::.|::|.||
Yeast    67 TKQLAEDSNNLRSNNENYTK--KNQDL--EQQLEDSEAKLKEAMDKLKEADLNSEQMGRRIVALE 127

Human   174 GELERSEERAEVAESRARQLEEELRTMDQALKSL 207
            .|.:..|::.|..:|:..:.::||..:..:|::|
Yeast   128 EERDEWEKKCEEFQSKYEEAQKELDEIANSLENL 161

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TPM2	XP_016870577.1	CwlO1	<1..>89	CDD:443091	12/44 (27%)
		Tropomyosin	48..>213	CDD:459736	41/160 (26%)
TPM2	NP_012128.3	Tropomyosin_1	7..148	CDD:403808	37/140 (26%)