Protein Alignment TNS1 and Pten

DIOPT Version :9

• Sequence 1: XP_024308847.1
• Gene: TNS1 / 7145
• HGNCID: 11973
• Length: 2005
• Species: Homo sapiens
• Sequence 2: NP_001162933.1
• Gene: Pten / 43991
• FlyBaseID: FBgn0026379
• Length: 514
• Species: Drosophila melanogaster
• Alignment Length: 550
• Identity: 137/550 - (24%)
• Similarity: 215/550 - (39%)
• Gaps: 151/550 - (27%)

Human   123 IRNMSVS----RTMEDSCELDLVYVTERIIAVSFPSTANEEN-FRSNLREVAQMLKSKHGGNYLL 182
            |||: ||    |..|...:|||.|:.:.|||:.:|:....|. ||:.|.:|.::|:..|..:|.:
  Fly    12 IRNV-VSKKRIRYKEKGYDLDLTYINDNIIAMGYPAPDKLEGLFRNRLEDVFKLLEENHAQHYKI 75

Human   183 FNL-SERRPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRIG 246
            :|| |||..|:.|...:|..:.:.|.:.|.:|.|...|..:|.||..|..|||.:|.|..:||.|
  Fly    76 YNLCSERSYDVAKFRGRVAVYPFDDHNPPTIELIQRFCSDVDMWLKEDSSNVVAVHCKAGKGRTG 140

Human   247 VVIAAYMHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIKMNNKPLFL 311
            .:|.||:.:|.|..|||:||..:..||..:.|.|.|  |||||||.|||.|:..|:..:...|.:
  Fly   141 TMICAYLVFSGIKKSADEALAWYDEKRTKDRKGVTI--PSQRRYVQYFSKLVCSSVPYSKVSLNV 203

Human   312 HHVIMHGIPNFESKGGCRPFLRIYQ-AMQPVYTSGIYN--------IPGDSQTSVCITIEPGLLL 367
            ..:..       |:..|...|.:.: ::..::.|...|        :|.|.|.|..:||:|.:.:
  Fly   204 CEIRF-------SESSCVQNLGMVECSISVLHDSATENAKPDRLKTLPIDFQKSFVLTIKPSIPV 261

Human   368 KGDILLKCYHKKFRSPAR-------DVIFRVQFHTCA--------IHDLGVVFGKEDLDDAFKDD 417
            .||:..:...|   ||.:       :..|...:..|.        ||.|    .|.::||..||.
  Fly   262 SGDVKFELTKK---SPDKIICHFWLNTFFVRNYSPCESDGTVNKYIHTL----SKSEIDDVHKDS 319

Human   418 ---RFPEYGKVEFVFSYGPEKIQGMEHLENGPSVSVDYNTSDPLIRWDSYDNFSGHRDDGMEGAV 479
               ||.|..|:..||.        .|:..|    .|....|:.            .|::.:....
  Fly   320 EHKRFSEEFKISIVFE--------AENFSN----DVQAEASEK------------ERNENVLNFE 360

Human   480 RSDFDMKAQSFSALSFFPAFLSLSAHCLRTFEKQMGAPHVMQRQKGPRVVPWLLSAMQACASWFG 544
            |||:|                |||.:|
  Fly   361 RSDYD----------------SLSPNC-------------------------------------- 371

Human   545 GLCIKVVGHTQGPLDGSLYAKVKKKDSLHGSTGAVNATRPTLSATPNHVEHTLSVSSDSGNSTAS 609
                              ||:.|...::...    |.|:.....|.:|.:....:..|:..::.:
  Fly   372 ------------------YAEKKVLTAIVND----NTTKSQTIETLDHKDIVTKIQYDTSTNSKN 414

Human   610 TKTDKTDEPVPGASSATAALSPQEKRELDR 639
            |.| ......|.:.:...:|:...|.|:.|
  Fly   415 TST-ACKRKQPNSKTLLPSLNDSTKEEIKR 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TNS1	XP_024308847.1	None
Pten	NP_001162933.1	PTPc	58..167	CDD:304379	40/108 (37%)
		PTEN_C2	196..335	CDD:287393	33/152 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2283
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810