Protein Alignment TNNT2 and tnnt2a

DIOPT Version :9

• Sequence 1: NP_001263274.1
• Gene: TNNT2 / 7139
• HGNCID: 11949
• Length: 298
• Species: Homo sapiens
• Sequence 2: NP_690853.1
• Gene: tnnt2a / 58071
• ZFINID: ZDB-GENE-000626-1
• Length: 282
• Species: Danio rerio
• Alignment Length: 296
• Identity: 198/296 - (66%)
• Similarity: 235/296 - (79%)
• Gaps: 18/296 - (6%)

Human     1 MSDIEEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEA 65
            |||.|| ||||||:|:|:  |||||:.:|:....|||.:|  |.....|||..|.|.||    |.
Zfish     1 MSDNEE-VEEYEEQEEEQ--VEEEEEVQEEAQHDEEAQQE--ENAGGDEETTQEHDGEE----ET 56

Human    66 EDGPMEESKPK-PRSFM-PNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEE 128
            |||. ||:||| .:.|| ||||||||||||||||||||||||||||||||.|||||||:||||||
Zfish    57 EDGG-EEAKPKFLKPFMLPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQTLIEAHFESRKKEEE 120

Human   129 ELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMH 193
            |::|||||||:||:|||||||||:|||:|||.||.|||||:||||.:::|||:|:|||.|:: :|
Zfish   121 EIISLKDRIEKRRSERAEQQRIRSERERERQKRLEEERARKEEEEAKKRAEDDAKKKKTLTS-LH 184

Human   194 FGGYIQKQAQTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKF 258
            ||||:||   .||:|||:||||||||||..:|||.|.||:.||..|||||||||..:..||||||
Zfish   185 FGGYMQK---IERRSGKKQTEREKKKKIFGDRRKPLDIDNANESALREKAKELWSWMRELEAEKF 246

Human   259 DLQEKFKQQKYEINVLRNRINDNQKVSK--TRGKAK 292
            :||.:|.:|||||||||||::|:||.||  .||..|
Zfish   247 ELQYQFGKQKYEINVLRNRVSDHQKTSKRTKRGLRK 282

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TNNT2	NP_001263274.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..95		54/95 (57%)
		Troponin	103..241	CDD:307228	99/137 (72%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	120..219		70/98 (71%)
tnnt2a	NP_690853.1	Troponin	95..229	CDD:279349	99/137 (72%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C194337211
Domainoid	1	1.000	193	1.000	Domainoid score	I13423
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H68050
Inparanoid	1	1.050	353	1.000	Inparanoid score	I8647
NCBI	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG40645
OrthoDB	1	1.010	-	-		D1480247at2759
OrthoFinder	1	1.000	-	-		FOG0001446
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_113610
Panther	1	1.100	-	-	LDO	PTHR11521
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X9722
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	1	1.500	-	-
	14	14.370