Protein Alignment TNNT2 and tnt-2

DIOPT Version :10

• Sequence 1: NP_001263274.1
• Gene: TNNT2 / 7139
• HGNCID: 11949
• Length: 298
• Species: Homo sapiens
• Sequence 2: NP_001024703.1
• Gene: tnt-2 / 181119
• WormBaseID: WBGene00006587
• Length: 428
• Species: Caenorhabditis elegans
• Alignment Length: 325
• Identity: 99/325 - (30%)
• Similarity: 162/325 - (49%)
• Gaps: 67/325 - (20%)

Human     1 MSDIEEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEA 65
            |||.|||:...||||.||:..||.        |:||||.|||.||           |||.||.|
 Worm     1 MSDEEEVLSGEEEEEVEESLAEEV--------EEEEAAAEDAAAE-----------EEEPEAAE- 45

Human    66 EDGPMEESKPKPRSFMPNLVPP-KIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRK---KE 126
            |:.|:|| |||||..:....|| ::.:.|....  ..:||.|::  |...|::  :|.|:   ||
 Worm    46 EEAPVEE-KPKPRPPVQEEKPPAEMTEAEAAML--AAKKRHEEE--EAAKLLD--YEQRRVLEKE 103

Human   127 --EEELVSLKDRIERRRAERAEQQR---IRNEREKERQNRLAEERARREEEENRRKAEDEARKKK 186
              |:||..||::.|:|||||.|.:|   .|..:::||:.:..|:|..:.:.|..||.|:::|:::
 Worm   104 QMEQELRELKEKQEKRRAEREEDERQFAERRRQDEERRRKDEEDRKAKADAEKARKNEEKSRRQQ 168

Human   187 ALSNMM-----------------------HFGGYIQKQAQTERKSG-KRQTEREKKKKILAERRK 227
            .::...                       :||..    ||..:..| .::.:.:.|:..|....|
 Worm   169 MMAGSFAGAAVGAPGGKNFTVSNKGDQAANFGNL----AQGAKAEGLTKEQQEDAKRAFLNVVCK 229

Human   228 VLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGKAK 292
            ...:..|..:.|:|:.|.:...|..||.||:||:::.::|:|::..|..|   .::|::.:...|
 Worm   230 AQDVSTLMPNDLKERIKGIHARIVKLEGEKYDLEKRRERQEYDLKELNER---QRQVARNKALKK 291

Human   293  292
             Worm   292  291

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TNNT2	NP_001263274.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..95		42/94 (45%)
		Troponin	103..241	CDD:460018	42/169 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	120..219		32/130 (25%)
tnt-2	NP_001024703.1	Troponin	213..>277	CDD:460018	16/63 (25%)