Protein Alignment TNNT2 and mup-2

DIOPT Version :10

• Sequence 1: NP_001263274.1
• Gene: TNNT2 / 7139
• HGNCID: 11949
• Length: 298
• Species: Homo sapiens
• Sequence 2: NP_509076.1
• Gene: mup-2 / 180914
• WormBaseID: WBGene00003495
• Length: 405
• Species: Caenorhabditis elegans
• Alignment Length: 307
• Identity: 91/307 - (29%)
• Similarity: 148/307 - (48%)
• Gaps: 67/307 - (21%)

Human     1 MSDIEEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEA 65
            |||.|||   |.:||.||..|||.|:...:.:|.||..|| ..|..|.:|.||
 Worm     1 MSDEEEV---YSDEEVEEEEVEETEEAPAEAEEPEETTEE-VVAPPEVKERRA------------ 49

Human    66 EDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRK---KE- 126
               |::|.||          |.::.:.|....  ..:||.|::  |...|::  :|.|:   ||
 Worm    50 ---PVQEEKP----------PAEMTEAEIAML--AAKKRHEEE--EAAKLLD--YEQRRVLEKEQ 95

Human   127 -EEELVSLKDRIERRRAERAEQQR---IRNEREKERQNRLAEERARREEEENRRKAEDEARKKKA 187
             |:||..||::.|:|||||.|.:|   .|..::.||:.:..:||..:.:.|..||.|::.|:::.
 Worm    96 IEQELRELKEKQEKRRAEREEDERQFAERRRQDDERRRKEEDERKAKADAEKIRKNEEKVRRQQM 160

Human   188 LSNMMHFGGYIQ--------------KQAQ----TERKSGKRQTEREK----KKKILAERRKVLA 230
            ::..  |.|.::              :.||    .:.|.||....:|:    |:..||...:|..
 Worm   161 MAGA--FNGRVEAGAGRNFTVASKGDQAAQFGNLAQAKGGKDVMSKEQMEDAKRNFLAAVCRVQD 223

Human   231 IDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNR 277
            :..|..:.|:|:.:.|...|..|||||:||:::.::|.|::..|..|
 Worm   224 VSGLLPNDLKERIRGLHARIVKLEAEKYDLEKRRERQDYDMKELHER 270

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TNNT2	NP_001263274.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..95		31/93 (33%)
		Troponin	103..241	CDD:460018	46/167 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	120..219		35/128 (27%)
mup-2	NP_509076.1	Troponin	204..>267	CDD:460018	19/62 (31%)