Protein Alignment TNNT2 and tnnt2

DIOPT Version :10

• Sequence 1: NP_001263274.1
• Gene: TNNT2 / 7139
• HGNCID: 11949
• Length: 298
• Species: Homo sapiens
• Sequence 2: XP_012809815.1
• Gene: tnnt2 / 100493699
• XenbaseID: XB-GENE-482614
• Length: 279
• Species: Xenopus tropicalis
• Alignment Length: 304
• Identity: 189/304 - (62%)
• Similarity: 227/304 - (74%)
• Gaps: 31/304 - (10%)

Human     1 MSDIEEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEA 65
            |||.|:::||||||::    |.|.|       |.||..|||...|...||...|.:|:|
 Frog     1 MSDTEDIIEEYEEEDK----VSENE-------EGEEEPEEDGNEEEANEEKEGENEEQE------ 48

Human    66 EDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEEL 130
                 |||:|||:.|||||:|.||||||:|||||||||||||||.|||.|||.|||:||||||||
 Frog    49 -----EESRPKPKLFMPNLIPLKIPDGEKVDFDDIHRKRMEKDLTELQTLIEVHFESRKKEEEEL 108

Human   131 VSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHFG 195
            .:|.:|:|:||||||||.|||||||||||.|:||||||:||||||::|||:.|||||.|||:|||
 Frog   109 QALTERMEKRRAERAEQLRIRNEREKERQARVAEERARKEEEENRKRAEDDVRKKKAFSNMLHFG 173

Human   196 GYIQKQAQTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDL 260
            ||:||   ||||.||:||||||||.||.||:..|.|.::|||:||.:|:.|:..||.|||||:|.
 Frog   174 GYLQK---TERKVGKKQTEREKKKMILTERKTPLNIGNMNEDKLRTEAQHLFNRIYELEAEKYDH 235

Human   261 QEKFKQQKYEINVLRNRINDNQKV-SKT-----RGKAKVTGRWK 298
            |..||:|||||||||||::|:||: ||:     .||..|.||||
 Frog   236 QATFKKQKYEINVLRNRVSDHQKLKSKSSKGPRSGKGIVGGRWK 279

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TNNT2	NP_001263274.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..95		43/93 (46%)
		Troponin	103..241	CDD:460018	101/137 (74%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	120..219		75/98 (77%)
tnnt2	XP_012809815.1	Troponin	81..215	CDD:460018	100/136 (74%)