Protein Alignment TNNI2 and wupA

DIOPT Version :10

• Sequence 1: NP_003273.1
• Gene: TNNI2 / 7136
• HGNCID: 11946
• Length: 182
• Species: Homo sapiens
• Sequence 2: NP_728142.1
• Gene: wupA / 32794
• FlyBaseID: FBgn0283471
• Length: 269
• Species: Drosophila melanogaster
• Alignment Length: 176
• Identity: 57/176 - (32%)
• Similarity: 96/176 - (54%)
• Gaps: 17/176 - (9%)

Human    14 RRQHLKSVMLQIAATELEKEESRREAEKQNYLAEHC-PPLHI-PGSMSEVQELCKQLHAKIDAAE 76
            |::.|:.::.:.||.||:||:.|:.||::..:.|.| .|.:: ..|..|:||:|::.:.::...|
  Fly   104 RKKKLRLLLRKKAAEELKKEQERKAAERRRIIEERCGSPRNLSDASEGELQEICEEYYERMYICE 168

Human    77 EEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSADAMLKALLGSKHKVCMDLRANL 141
            .:|:|:|..|:|...|:.|:|.::.||||||.:|.|::|....:...|.   .|.....:.|..|
  Fly   169 GQKWDLEYEVRKKDWEINDLNAQVNDLRGKFVKPALKKVSKYENKFAKL---QKKAAEFNFRNQL 230

Human   142 KQVKK-----EDTEKERDLRDVGDWRKNIEEKSGMEGRKKMFESES 182
            |.|||     |:.|||:.    .||.|.   |.|....|:..|:|:
  Fly   231 KVVKKKEFTLEEEEKEKK----PDWSKG---KPGDAKVKEEVEAEA 269

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TNNI2	NP_003273.1	Involved in binding TNC	2..48		11/33 (33%)
		Troponin	15..145	CDD:460018	41/131 (31%)
		Involved in binding TNC and actin	97..117		10/19 (53%)
wupA	NP_728142.1	Troponin	116..233	CDD:460018	40/119 (34%)