DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment TNFAIP6 and NimB4

DIOPT Version :9

Sequence 1:NP_009046.2 Gene:TNFAIP6 / 7130 HGNCID:11898 Length:277 Species:Homo sapiens
Sequence 2:NP_788046.1 Gene:NimB4 / 34814 FlyBaseID:FBgn0028542 Length:448 Species:Drosophila melanogaster


Alignment Length:206 Identity:43/206 - (20%)
Similarity:57/206 - (27%) Gaps:93/206 - (45%)


- Green bases have known domain annotations that are detailed below.


Human    45 GKYKLTYAEAKAVCEFEGGHLATYKQLEAARKIGFHVCAAGWMAKGRVG-----YPIVKPGPNCG 104
            |..|....:..|.|    ||      .|...:.|...||.|:....|..     .||..  |:||
  Fly   202 GSRKFCQPQCNATC----GH------NEVCLEPGKCSCAEGYTRGLRESAALGCQPICI--PDCG 254

Human   105 FGKTGIIDYGIRLNRSERWDAYCYNPHAKECGGVFTDPKQIFKSPGFPNEYEDNQI-----CYWH 164
            :|                   :|..|:..||            .|||  :...|.|     ||..
  Fly   255 YG-------------------HCVRPNECEC------------FPGF--QKRKNGITCEGDCYMT 286

Human   165 IR-----------LKYGQRIHLSFLDFDLEDDPGCLADYVEIYDSYDDVHGFVGRYCGDELPDDI 218
            ..           .:.|.|       :| ::...||.|                  |||...:.:
  Fly   287 CENGFCANKTTCVCQNGYR-------YD-KNTTTCLPD------------------CGDNCDNGV 325

Human   219 -ISTGNVMTLK 228
             ||.||....|
  Fly   326 CISPGNCRCFK 336

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TNFAIP6NP_009046.2 Link_domain_TSG_6_like 36..128 CDD:239592 18/87 (21%)
CUB 135..244 CDD:278839 22/111 (20%)
NimB4NP_788046.1 None


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1218
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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