DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment TNFAIP6 and NimB2

DIOPT Version :9

Sequence 1:NP_009046.2 Gene:TNFAIP6 / 7130 HGNCID:11898 Length:277 Species:Homo sapiens
Sequence 2:NP_723857.1 Gene:NimB2 / 260645 FlyBaseID:FBgn0028543 Length:421 Species:Drosophila melanogaster


Alignment Length:144 Identity:39/144 - (27%)
Similarity:44/144 - (30%) Gaps:51/144 - (35%)


- Green bases have known domain annotations that are detailed below.


Human    32 ERAAGVYHR-------EARSGKYKLTYAEAKAVCEFEGGHLATYKQLEAARK--------IGFHV 81
            ||...:|.|       :.|:|     ...|...|....||:.|     |..|        .|..|
  Fly   172 ERNPHIYRRCEPICADDCRNG-----ICTAPNTCVCIPGHVRT-----AEGKCISTCPLGCGNGV 226

Human    82 CAAGWMAKGRVGY-----------PIVKPGPNCGFG------KTGIIDYGIRLNRSERWDAYCYN 129
            |......|.|.||           |..|||  |.||      |...:| |.||..    |..| .
  Fly   227 CDERNECKCREGYSLEPETRKYCQPECKPG--CSFGRCVAPNKCACLD-GYRLAA----DGSC-E 283

Human   130 PHAKEC-GGVFTDP 142
            |....| .|..|.|
  Fly   284 PVCDSCENGKCTAP 297

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TNFAIP6NP_009046.2 Link_domain_TSG_6_like 36..128 CDD:239592 31/123 (25%)
CUB 135..244 CDD:278839 4/9 (44%)
NimB2NP_723857.1 None


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1218
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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