DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tssk4 and par-1

DIOPT Version :9

Sequence 1:	NP_001240817.1	Gene:	Tssk4 / 71099	MGIID:	1918349	Length:	338	Species:	Mus musculus
Sequence 2:	NP_995894.2	Gene:	par-1 / 2768852	FlyBaseID:	FBgn0260934	Length:	1170	Species:	Drosophila melanogaster

Alignment Length:	313	Identity:	109/313 - (34%)
Similarity:	166/313 - (53%)	Gaps:	33/313 - (10%)

- Green bases have known domain annotations that are detailed below.

Mouse     2 GKGDTSETASATPAYRSVMEEYG-YEVGKIIGHGSYGTVYEAYYTKQKVMVAVKIISKKKASEDY 65
            |..:....:||...:|:..|..| |::.|.||.|::..|..|.:......||:|||.|.:.:...
  Fly   229 GSPNMQMRSSAPMRWRATEEHIGKYKLIKTIGKGNFAKVKLAKHLPTGKEVAIKIIDKTQLNPGS 293

Mouse    66 LNKFLPREIQVMKVLRHKYLINFYQAIETTSRVYIILELAQGGDVLEWIQRYGACAETLAGKWFS 130
            |.| |.||:::||:|.|..::..:|.|||...:|:|:|.|.||:|.:::..:|...|..|...|.
  Fly   294 LQK-LFREVRIMKMLDHPNIVKLFQVIETEKTLYLIMEYASGGEVFDYLVLHGRMKEKEARVKFR 357

Mouse   131 QMALGIAYLHSKGIVHRLTPSLSAAGRDLKLENLLLDKRENVKISDFGFA-KMVPSSQPVHSSPS 194
            |:...:.|.|.|.|:|          ||||.||||||...|:||:||||: :..|.|:
  Fly   358 QIVSAVQYCHQKRIIH----------RDLKAENLLLDSELNIKIADFGFSNEFTPGSK------- 405

Mouse   195 YRQMNSLSHLSQTYCGSFAYACPEILLGLPYNPFLSDTWSMGVILYTLVVARLPFDDTNLKKLLR 259
                      ..|:|||..||.||:..|..|:....|.||:||||||||...||||.:.|:: ||
  Fly   406 ----------LDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGSTLRE-LR 459

Mouse   260 ETQKEVTFPANLTISQECKNLILQ-LLRQSTKRATILDVLRDPWM-LKFQPEQ 310
            |......:.....:|.:|:||:.: |:....|||::..::.|.|| :.|:.::
  Fly   460 ERVLRGKYRIPFYMSTDCENLLRKFLVLNPAKRASLETIMGDKWMNMGFEEDE 512

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tssk4	NP_001240817.1	STKc_TSSK4-like	24..302	CDD:271064	101/280 (36%)
Tssk4	NP_001240817.1	S_TKc	25..303	CDD:214567	100/279 (36%)
par-1	NP_995894.2	STKc_MARK	252..504	CDD:270974	100/280 (36%)
		S_TKc	253..504	CDD:214567	100/279 (36%)
		UBA_MARK_Par1	525..563	CDD:270522
		MARK1-3_C	839..936	CDD:213381
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910