Protein Alignment TSPAN8 and Tsp5D

DIOPT Version :9

• Sequence 1: NP_001356689.1
• Gene: TSPAN8 / 7103
• HGNCID: 11855
• Length: 237
• Species: Homo sapiens
• Sequence 2: NP_001259266.1
• Gene: Tsp5D / 31540
• FlyBaseID: FBgn0029837
• Length: 287
• Species: Drosophila melanogaster
• Alignment Length: 260
• Identity: 64/260 - (24%)
• Similarity: 117/260 - (45%)
• Gaps: 37/260 - (14%)

Human     7 CIKYSMFTFNFLFWLCGILILALAIWVRVSNDSQAIFGSEDVGSSSYVAVDILIAVGAIIMILGF 71
            ||:.:....|.:.|||....|...:|:|:|....|....:..|.|   |..|.:.:|....::.|
  Fly     8 CIRRTFCWLNIILWLCSCAFLGAGLWLRLSYAGYATLLPQHAGLS---ADTIFMGIGGTGFVVSF 69

Human    72 LGCCGAIKESRCMLLLFFIGLLLILLLQVATGILGAVFKSKSDRIVNETL-------YENTKLLS 129
            .|||||..:|||:|:|:|:.::::.:.:...|.:..:|:....|.:...|       |.::...|
  Fly    70 FGCCGAWVQSRCLLVLYFMLIVMLFMSEFLVGSIAFLFRGGLGRTLANELRFGIERHYNSSDRGS 134

Human   130 ATGESEKQFQEAIIVFQEEFKCCGLVNGAADWGNNFQHYP-------ELCACLDKQR-------- 179
            ....|.....:::   |:.|:||| |:...|| .:.|.:|       ..|..|..||
  Fly   135 LVAPSVASIWDSV---QQSFECCG-VSSYEDW-YDIQSWPGRRWVPESCCRTLYDQRQVLTEGSG 194

Human   180 ------PC-QSYNGKQVYKETCISFIKDFLAKNLIIVIGISFGLAVIEILGLVFSMVLYCQIGNK 237
                  .| :|.|....:.:.|...::.:....|.:|..:..|:|.:::.||:.||:|:|.:.:|
  Fly   195 DGMMRPDCGRSENPSLWWDKGCAHSLQSWFTGQLNVVGAVGLGIAFVQLFGLITSMLLFCTVKHK 259

Human   238  237
              Fly   260  259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TSPAN8	NP_001356689.1	Tetraspannin	8..230	CDD:334016	60/250 (24%)
		TM4SF3_like_LEL	106..206	CDD:239407	24/128 (19%)
Tsp5D	NP_001259266.1	Tetraspannin	8..256	CDD:278750	63/255 (25%)
		NET-5_like_LEL	105..228	CDD:239418	24/127 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X124
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910