Protein Alignment NR2E1 and Nr2e1

DIOPT Version :10

• Sequence 1: NP_001273031.1
• Gene: NR2E1 / 7101
• HGNCID: 7973
• Length: 422
• Species: Homo sapiens
• Sequence 2: NP_689415.1
• Gene: Nr2e1 / 21907
• MGIID: 1100526
• Length: 385
• Species: Mus musculus
• Alignment Length: 385
• Identity: 374/385 - (97%)
• Similarity: 376/385 - (97%)
• Gaps: 3/385 - (0%)

Human    41 LESPGG---RILDIPCKVCGDRSSGKHYGVYACDGCSGFFKRSIRRNRTYVCKSGNQGGCPVDKT 102
            :..|.|   ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse     1 MSKPAGSTSRILDIPCKVCGDRSSGKHYGVYACDGCSGFFKRSIRRNRTYVCKSGNQGGCPVDKT 65

Human   103 HRNQCRACRLKKCLEVNMNKDAVQHERGPRTSTIRKQVALYFRGHKEENGAAAHFPSAALPAPAF 167
            |||||||||||||||||||||||||||||||||||||||||||||||:|||||||||.|||||||
Mouse    66 HRNQCRACRLKKCLEVNMNKDAVQHERGPRTSTIRKQVALYFRGHKEDNGAAAHFPSTALPAPAF 130

Human   168 FTAVTQLEPHGLELAAVSTTPERQTLVSLAQPTPKYPHEVNGTPMYLYEVATESVCESAARLLFM 232
            ||||||||||||||||||.||||||||||||||||||||||||||||||||||||||||||||||
Mouse   131 FTAVTQLEPHGLELAAVSATPERQTLVSLAQPTPKYPHEVNGTPMYLYEVATESVCESAARLLFM 195

Human   233 SIKWAKSVPAFSTLSLQDQLMLLEDAWRELFVLGIAQWAIPVDANTLLAVSGMNGDNTDSQKLNK 297
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||.||||||||||
Mouse   196 SIKWAKSVPAFSTLSLQDQLMLLEDAWRELFVLGIAQWAIPVDANTLLAVSGMNTDNTDSQKLNK 260

Human   298 IISEIQALQEVVARFRQLRLDATEFACLKCIVTFKAVPTHSGSELRSFRNAAAIAALQDEAQLTL 362
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   261 IISEIQALQEVVARFRQLRLDATEFACLKCIVTFKAVPTHSGSELRSFRNAAAIAALQDEAQLTL 325

Human   363 NSYIHTRYPTQPCRFGKLLLLLPALRSISPSTIEEVFFKKTIGNVPITRLLSDMYKSSDI 422
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   326 NSYIHTRYPTQPCRFGKLLLLLPALRSISPSTIEEVFFKKTIGNVPITRLLSDMYKSSDI 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NR2E1	NP_001273031.1	NR_DBD_TLX	45..136	CDD:143537	89/93 (96%)
		NR_LBD_Tlx_PNR_like	191..406	CDD:132748	213/214 (100%)
Nr2e1	NP_689415.1	NR_DBD_TLX	8..99	CDD:143537	88/90 (98%)
		NR_LBD_Tlx_PNR_like	154..369	CDD:132748	213/214 (100%)
		Required for transcriptional repression	341..385		43/43 (100%)