DRSC/TRiP Functional Genomics Resources

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Protein Alignment NR2E1 and nr2e1

DIOPT Version :10

Sequence 1:NP_001273031.1 Gene:NR2E1 / 7101 HGNCID:7973 Length:422 Species:Homo sapiens
Sequence 2:XP_002937209.2 Gene:nr2e1 / 100491500 XenbaseID:XB-GENE-483554 Length:386 Species:Xenopus tropicalis


Alignment Length:386 Identity:357/386 - (92%)
Similarity:367/386 - (95%) Gaps:4/386 - (1%)


- Green bases have known domain annotations that are detailed below.


Human    41 LESPGG---RILDIPCKVCGDRSSGKHYGVYACDGCSGFFKRSIRRNRTYVCKSGNQGGCPVDKT 102
            :..|.|   |||||||||||||||||||||||||||||||||||||||:|||||||||||.||||
 Frog     1 MSKPTGSTSRILDIPCKVCGDRSSGKHYGVYACDGCSGFFKRSIRRNRSYVCKSGNQGGCLVDKT 65

Human   103 HRNQCRACRLKKCLEVNMNKDAVQHERGPRTSTIRKQVALYFRGHKEENGAAAHFPSAALPAPAF 167
            |||||||||||||||||||||||||||||||||||||||||||||||.||:..||||||||||.|
 Frog    66 HRNQCRACRLKKCLEVNMNKDAVQHERGPRTSTIRKQVALYFRGHKEINGSTPHFPSAALPAPTF 130

Human   168 FTAVTQLEPHGLELAAVSTTPERQTLVSLAQPTPKYPHEVNGTPMYLYEVATESVCESAARLLFM 232
            ||.|:|||||.|||.|:||||||||||.||||||||||||||.|:||||||||||||||||||||
 Frog   131 FTTVSQLEPHNLELTAISTTPERQTLVGLAQPTPKYPHEVNGAPLYLYEVATESVCESAARLLFM 195

Human   233 SIKWAKSVPAFSTLSLQDQLMLLEDAWRELFVLGIAQWAIPVDANTLLAVSGMNGDNTDSQKLNK 297
            ||||||||||||||||||||||||||||||||||||||||||||:|||||||||.|||:||||||
 Frog   196 SIKWAKSVPAFSTLSLQDQLMLLEDAWRELFVLGIAQWAIPVDASTLLAVSGMNSDNTESQKLNK 260

Human   298 IISEIQALQEVVARFRQLRLDATEFACLKCIVTFKA-VPTHSGSELRSFRNAAAIAALQDEAQLT 361
            ||||||||||||:||||||||||||||||||||||| ||.|||||||||||||||||||||||||
 Frog   261 IISEIQALQEVVSRFRQLRLDATEFACLKCIVTFKAGVPPHSGSELRSFRNAAAIAALQDEAQLT 325

Human   362 LNSYIHTRYPTQPCRFGKLLLLLPALRSISPSTIEEVFFKKTIGNVPITRLLSDMYKSSDI 422
            |||||||||||||||||||||||||||||:|||||||||||||||||||||||||||||||
 Frog   326 LNSYIHTRYPTQPCRFGKLLLLLPALRSINPSTIEEVFFKKTIGNVPITRLLSDMYKSSDI 386

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
NR2E1NP_001273031.1 NR_DBD_TLX 45..136 CDD:143537 87/93 (94%)
NR_LBD_Tlx_PNR_like 191..406 CDD:132748 205/215 (95%)
nr2e1XP_002937209.2 NR_DBD_TLX 8..99 CDD:143537 86/90 (96%)
NR_LBD_Tlx_PNR_like 154..370 CDD:132748 205/215 (95%)

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