Protein Alignment ACTG1 and Arp53D

DIOPT Version :10

• Sequence 1: NP_001605.1
• Gene: ACTG1 / 71
• HGNCID: 144
• Length: 375
• Species: Homo sapiens
• Sequence 2: NP_477037.2
• Gene: Arp53D / 36879
• FlyBaseID: FBgn0011743
• Length: 411
• Species: Drosophila melanogaster
• Alignment Length: 381
• Identity: 244/381 - (64%)
• Similarity: 297/381 - (77%)
• Gaps: 11/381 - (2%)

Human     1 MEEEI------AALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQ 59
            |..|:      ||:|||||||:|||||:.:|.||||||||||||||..|::.....||.:|:.|.
  Fly    36 MSSEVDSNSHHAAVVIDNGSGVCKAGFSPEDTPRAVFPSIVGRPRHLNVLLDSVIGDSVIGEAAA 100

Human    60 SKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMF 124
            .||||||||||||||:|.|||:||.:|.|| |..||..|.:.|.||||||||||.||||||:|||
  Fly   101 RKRGILTLKYPIEHGMVKNWDEMEMVWQHT-YELLRADPMDLPALLTEAPLNPKKNREKMTEIMF 164

Human   125 ETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYL 189
            |.|..||.|||:||||||||:|||.|||:|||||||||||||||:|||||.:|:|||||||||||
  Fly   165 EHFQVPAFYVAVQAVLSLYATGRTVGIVVDSGDGVTHTVPIYEGFALPHACVRVDLAGRDLTDYL 229

Human   190 MKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNER 254
            .|:|.|||.:..|:|||||||:||||||||::::.:||    ......::|||||||.|.:|.||
  Fly   230 CKLLLERGVTMGTSAEREIVREIKEKLCYVSMNYAKEM----DLHGKVETYELPDGQKIVLGCER 290

Human   255 FRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITA 319
            |||||||||||.||.|..||||.|.:||..||:|:|||:|||.||||||||:..|..|..:::|.
  Fly   291 FRCPEALFQPSLLGQEVMGIHEATHHSITNCDMDLRKDMYANIVLSGGTTMFRNIEHRFLQDLTE 355

Human   320 LAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF 375
            :||.:::||:.|.|:|::|||.|||:||||::||.|||...||:|.|.:|||||||
  Fly   356 MAPPSIRIKVNASPDRRFSVWTGGSVLASLTSFQNMWIDSLEYEEVGSAIVHRKCF 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACTG1	NP_001605.1	ASKHA_NBD_actin	6..370	CDD:466823	235/363 (65%)
Arp53D	NP_477037.2	ASKHA_ATPase-like	47..406	CDD:483947	235/363 (65%)