back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment TIMP3 and Timp

DIOPT Version :10

Sequence 1:	NP_000353.1	Gene:	TIMP3 / 7078	HGNCID:	11822	Length:	211	Species:	Homo sapiens
Sequence 2:	NP_731461.1	Gene:	Timp / 41248	FlyBaseID:	FBgn0025879	Length:	210	Species:	Drosophila melanogaster

Alignment Length:	208	Identity:	58/208 - (27%)
Similarity:	99/208 - (47%)	Gaps:	31/208 - (14%)

- Green bases have known domain annotations that are detailed below.

Human     5 LGLIVLLGSWSLGDWG--AEACTCSPSHPQDAFCNSDIVIRAKVVGKKLVKEGPFGTLVYTIKQM 67
            |||:.||.......:|  |:||:|.|||||..|..:|.|::.:|:.|....|.  |...|.:...
  Fly     7 LGLLTLLLVAVFAFYGRPADACSCMPSHPQTHFAQADYVVQLRVLRKSDTIEP--GRTTYKVHIK 69

Human    68 KMYRGFT---KMPHVQYIHTEASESLCGLKLEVNKYQYLLTGRVYDGKMYT-GLCNFVERWDQLT 128
            :.|:..:   :|.....:.|...:::||:.|::.|. |::.||     |.| .:|::.:.:.::|
  Fly    70 RTYKATSEARRMLRDGRLSTPQDDAMCGINLDLGKV-YIVAGR-----MPTLNICSYYKEYTRMT 128

Human   129 LSQRKGLNYRYHLGCNCKIKSCYYLPCFVTSKN---ECLWTDMLSNFGYPGYQSKHYACIRQK-- 188
            :::|.|.:..|....||.:..|:...|| ..:|   .|.|    |.||  ..::.:.||:..|
  Fly   129 ITERHGFSGGYAKATNCTVTPCFGERCF-KGRNYADTCKW----SPFG--KCETNYSACMPHKVQ 186

Human   189 --GGY---CSWYR 196
              .|.   |.|.|
  Fly   187 TVNGVISRCRWRR 199

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.