Sequence 1: | NP_005415.1 | Gene: | TIE1 / 7075 | HGNCID: | 11809 | Length: | 1138 | Species: | Homo sapiens |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_524394.2 | Gene: | htl / 42160 | FlyBaseID: | FBgn0010389 | Length: | 729 | Species: | Drosophila melanogaster |
Alignment Length: | 825 | Identity: | 227/825 - (27%) |
---|---|---|---|
Similarity: | 340/825 - (41%) | Gaps: | 225/825 - (27%) |
- Green bases have known domain annotations that are detailed below.
Human 424 WECRVS------TSGGQDSRRFKVNVKVPPVPLAAPRLLTKQSRQLVVSPLVSFSGDGPISTVRL 482
Human 483 HYRPQDSTMDWSTIVVDPSENVTLMNLRPKTGYSVRVQLSRPGEGGEGAWGPP------------ 535
Human 536 TLMTTDC-----PEPLLQPWLEGWHVEGTDRLRVSWSLPLVPGPLVGDGFLLR-LWDGTRGQERR 594
Human 595 ENVSSPQARTALLTGLTPGT--HYQLDVQLYHCTLLGPASPPAHVLLPPSGPPAPRHLHAQALSD 657
Human 658 SEIQLTWKHPEALPGPIS-------------KYVVEVQVAGGAGDPLWIDVDRPEETS-TIIRGL 708
Human 709 NASTR---YLFRMRASIQGLGDWSNTVEESTLG--NGLQAEGPVQESRAAEEGLDQQLILAVVGS 768
Human 769 VSATCLT-----------ILAALLTLVCIRR----SCLHRRRTFTYQ----------SGSGEETI 808
Human 809 LQFSSGTLTLTRRPKL--------------QPEPLS---YPV-LEWE----DITFEDLIGEGNFG 851
Human 852 QVIRAMIKKDGLKMNA--AIKMLKEYASENDHRDFAGELEVLCKLGHHPNIINLLGACKNRGYLY 914
Human 915 IAIEYAPYGNLLDFLRKSRVLETDPAFAREHG----------TASTLSSRQLLRFASDAANGMQY 969
Human 970 LSEKQFIHRDLAARNVLVGENLASKIADFGLSR---GEEVYVKKTMGRLPVRWMAIESLNYSVYT 1031
Human 1032 TKSDVWSFGVLLWEIVSLGGTPY-CGMTCAELYEKLPQGYRMEQPRNCDDEVYELMRQCWRDRPY 1095
Human 1096 ERPPFAQIALQLGRMLEARKAYVNMSLFENFTYAGID---ATAEE 1137 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
TIE1 | NP_005415.1 | ig | 129..210 | CDD:278476 | |
EGF_CA | 227..256 | CDD:238011 | |||
EGF_2 | 315..344 | CDD:285248 | |||
ig | 356..441 | CDD:278476 | 6/22 (27%) | ||
fn3 | 452..536 | CDD:278470 | 15/95 (16%) | ||
fn3 | 548..632 | CDD:278470 | 19/86 (22%) | ||
FN3 | 644..736 | CDD:238020 | 21/108 (19%) | ||
PTKc_Tie1 | 836..1132 | CDD:270671 | 131/315 (42%) | ||
TyrKc | 839..1107 | CDD:197581 | 126/283 (45%) | ||
htl | NP_524394.2 | Ig | 112..191 | CDD:299845 | 27/133 (20%) |
IG_like | 113..191 | CDD:214653 | 27/132 (20%) | ||
IG_like | 205..289 | CDD:214653 | 17/91 (19%) | ||
PKc_like | 404..692 | CDD:304357 | 129/299 (43%) | ||
STYKc | 416..688 | CDD:214568 | 126/283 (45%) | ||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_KOG0200 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
2 | 1.810 |