| Sequence 1: | NP_005415.1 | Gene: | TIE1 / 7075 | HGNCID: | 11809 | Length: | 1138 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_035717.2 | Gene: | Tie1 / 21846 | MGIID: | 99906 | Length: | 1134 | Species: | Mus musculus |
| Alignment Length: | 1139 | Identity: | 1055/1139 - (92%) |
|---|---|---|---|
| Similarity: | 1089/1139 - (95%) | Gaps: | 6/1139 - (0%) |
- Green bases have known domain annotations that are detailed below.
|
Human 1 MVWRVPPFLLPILFLASHVGAAVDLTLLANLRLTDPQRFFLTCVSGEAGAGRGSDAWGPPLLLEK 65
Human 66 DDRIVRT-PPGPPLRLARNGSHQVTLRGFSKPSDLVGVFSCVGGAGARRTRVIYVHNSPGAHLLP 129
Human 130 DKVTHTVNKGDTAVLSARVHKEKQTDVIWKSNGSYFYTLDWHEAQDGRFLLQLPNVQPPSSGIYS 194
Human 195 ATYLEASPLGSAFFRLIVRGCGAGRWGPGCTKECPGCLHGGVCHDHDGECVCPPGFTGTRCEQAC 259
Human 260 REGRFGQSCQEQCPGISGCRGLTFCLPDPYGCSCGSGWRGSQCQEACAPGHFGADCRLQCQCQNG 324
Human 325 GTCDRFSGCVCPSGWHGVHCEKSDRIPQILNMASELEFNLETMPRINCAAAGNPFPVRGSIELRK 389
Human 390 PDGTVLLSTKAIVEPEKTTAEFEVPRLVLADSGFWECRVSTSGGQDSRRFKVNVKVPPVPLAAPR 454
Human 455 LLTKQSRQLVVSPLVSFSGDGPISTVRLHYRPQDSTMDWSTIVVDPSENVTLMNLRPKTGYSVRV 519
Human 520 QLSRPGEGGEGAWGPPTLMTTDCPEPLLQPWLEGWHVEGTDRLRVSWSLPLVPGPLVGDGFLLRL 584
Human 585 WDGTRGQERRENVSSPQARTALLTGLTPGTHYQLDVQLYHCTLLGPASPPAHVLLPPSGPPAPRH 649
Human 650 LHAQALSDSEIQLTWKHPEALPGPISKYVVEVQVAGGAGDPLWIDVDRPEETSTIIRGLNASTRY 714
Human 715 LFRMRASIQGLGDWSNTVEESTLGNGLQAEGPVQESRAAEEGLDQQLILAVVGSVSATCLTILAA 779
Human 780 LLTLVCIRRSCLHRRRTFTYQSGSGEETILQFSSGTLTLTRRPKLQPEPLSYPVLEWEDITFEDL 844
Human 845 IGEGNFGQVIRAMIKKDGLKMNAAIKMLKEYASENDHRDFAGELEVLCKLGHHPNIINLLGACKN 909
Human 910 RGYLYIAIEYAPYGNLLDFLRKSRVLETDPAFAREHGTASTLSSRQLLRFASDAANGMQYLSEKQ 974
Human 975 FIHRDLAARNVLVGENLASKIADFGLSRGEEVYVKKTMGRLPVRWMAIESLNYSVYTTKSDVWSF 1039
Human 1040 GVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRMEQPRNCDDEVYELMRQCWRDRPYERPPFAQIA 1104
Human 1105 LQLGRMLEARKAYVNMSLFENFTYAGIDATAEEA 1138 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| TIE1 | NP_005415.1 | ig | 129..210 | CDD:278476 | 73/80 (91%) |
| EGF_CA | 227..256 | CDD:238011 | 27/28 (96%) | ||
| EGF_2 | 315..344 | CDD:285248 | 28/28 (100%) | ||
| ig | 356..441 | CDD:278476 | 71/84 (85%) | ||
| fn3 | 452..536 | CDD:278470 | 75/83 (90%) | ||
| fn3 | 548..632 | CDD:278470 | 73/83 (88%) | ||
| FN3 | 644..736 | CDD:238020 | 78/91 (86%) | ||
| PTKc_Tie1 | 836..1132 | CDD:270671 | 294/295 (100%) | ||
| TyrKc | 839..1107 | CDD:197581 | 266/267 (100%) | ||
| Tie1 | NP_035717.2 | ig | 127..208 | CDD:278476 | 73/80 (91%) |
| IG_like | 131..210 | CDD:214653 | 71/78 (91%) | ||
| EGF_Lam | 225..263 | CDD:238012 | 36/37 (97%) | ||
| EGF_CA | 312..343 | CDD:238011 | 30/30 (100%) | ||
| ig | 353..439 | CDD:278476 | 71/85 (84%) | ||
| IG | 367..441 | CDD:214652 | 64/73 (88%) | ||
| fn3 | 447..518 | CDD:278470 | 62/70 (89%) | ||
| fn3 | 546..628 | CDD:278470 | 73/83 (88%) | ||
| FN3 | 640..732 | CDD:238020 | 78/91 (86%) | ||
| PTKc_Tie1 | 832..1128 | CDD:270671 | 294/295 (100%) | ||
| TyrKc | 835..1103 | CDD:197581 | 266/267 (100%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C83952012 | |
| Domainoid | 1 | 1.000 | 546 | 1.000 | Domainoid score | I6309 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG0200 | |
| HGNC | 1 | 1.500 | - | - | ||
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H3957 | |
| Inparanoid | 1 | 1.050 | 2189 | 1.000 | Inparanoid score | I1290 |
| Isobase | 1 | 0.950 | - | 0 | Normalized mean entropy | S4853 |
| NCBI | 1 | 1.000 | - | - | ||
| OMA | 1 | 1.010 | - | - | QHG43836 | |
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 1 | 1.000 | - | - | FOG0006344 | |
| OrthoInspector | 1 | 1.000 | - | - | oto114715 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_106288 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR24416 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 1 | 1.000 | - | - | X11087 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| 17 | 17.210 | |||||