Protein Alignment TIAL1 and Hrb87F

DIOPT Version :10

• Sequence 1: NP_001029097.1
• Gene: TIAL1 / 7073
• HGNCID: 11804
• Length: 392
• Species: Homo sapiens
• Sequence 2: NP_476806.2
• Gene: Hrb87F / 48535
• FlyBaseID: FBgn0004237
• Length: 385
• Species: Drosophila melanogaster
• Alignment Length: 349
• Identity: 79/349 - (22%)
• Similarity: 124/349 - (35%)
• Gaps: 110/349 - (31%)

Human    86 NGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMA 150
            ||....|:|:     |.|...:|       :|:|.|....|.:.:|:.|..:|.|.|..|:||..
  Fly     8 NGNYDDGEEI-----TEPEQLRK-------LFIGGLDYRTTDDGLKAHFEKWGNIVDVVVMKDPK 60

Human   151 TGKSKGYGFVSF---YNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQENNTKQLRFED 212
            |.:|:|:||:::   |...:|:||..|.    :.||.:....|..:............|:|
  Fly    61 TKRSRGFGFITYSQSYMIDNAQNARPHK----IDGRTVEPKRAVPRQEIDSPNAGATVKKL---- 117

Human   213 VVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEK------GYSFVRFSTHESAA 271
                        :.||:.....::.:|:.|..||||:.:.:..:|      |::|:.|..::...
  Fly   118 ------------FVGGLRDDHDEECLREYFKDFGQIVSVNIVSDKDTGKKRGFAFIEFDDYDPVD 170

Human   272 HAIV----SVNGTTIEGHVVKCY-----------WGKESPDMTKNFQQVDYSQ----W------- 310
            ..|:    |:...|::  |.|..           .|:..|.......|.|..|    |
  Fly   171 KIILQKTHSIKNKTLD--VKKAIAKQDMDRQGGGGGRGGPRAGGRGGQGDRGQGGGGWGGQNRQN 233

Human   311 --GQWSQV------------YGNPQQYGQYMANGWQVPPYGVYGQPWNQQGFGVDQSPSAAWMGG 361
              |.|...            :|..|..|   :.||. ...|..|.|||.||.|     :..|.||
  Fly   234 GGGNWGGAGGGGGFGNSGGNFGGGQGGG---SGGWN-QQGGSGGGPWNNQGGG-----NGGWNGG 289

Human   362 FGAQPPQGQAPPPVIPPPNQAGYG 385
            .|                  .|||
  Fly   290 GG------------------GGYG 295

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TIAL1	NP_001029097.1	RRM1_TIAR	10..107	CDD:410028	6/20 (30%)
		RRM2_TIAR	113..192	CDD:410029	25/81 (31%)
		RRM3_TIAR	222..294	CDD:241064	18/92 (20%)
Hrb87F	NP_476806.2	RRM1_hnRNPA_like	25..102	CDD:409992	26/87 (30%)
		RRM_SF	116..188	CDD:473069	16/89 (18%)