Protein Alignment TIAL1 and Hrb98DE

DIOPT Version :10

• Sequence 1: NP_001029097.1
• Gene: TIAL1 / 7073
• HGNCID: 11804
• Length: 392
• Species: Homo sapiens
• Sequence 2: NP_524543.1
• Gene: Hrb98DE / 43385
• FlyBaseID: FBgn0001215
• Length: 365
• Species: Drosophila melanogaster
• Alignment Length: 288
• Identity: 64/288 - (22%)
• Similarity: 109/288 - (37%)
• Gaps: 71/288 - (24%)

Human   101 TTPSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNK 165
            |.|...:|       :|:|.|....|.|::|:.|..:|.|.|..|:||..|.:|:|:||:::.:.
  Fly    25 TEPEHMRK-------LFIGGLDYRTTDENLKAHFEKWGNIVDVVVMKDPRTKRSRGFGFITYSHS 82

Human   166 L---DAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCG 227
            .   :|:.:..|.    :.||.:....|..:............|:|                :.|
  Fly    83 SMIDEAQKSRPHK----IDGRVVEPKRAVPRQDIDSPNAGATVKKL----------------FVG 127

Human   228 GIASGLTDQLMRQTFSPFGQIMEIRVFPEK------GYSFVRFSTHESAAHAIV----SVNGTTI 282
            .:.....:|.:|..|..||.|::|.:..:|      |::||.|..::.....::    .:||..:
  Fly   128 ALKDDHDEQSIRDYFQHFGNIVDINIVIDKETGKKRGFAFVEFDDYDPVDKVVLQKQHQLNGKMV 192

Human   283 EGHVVKCYWGKESPDMTKNFQQ------------VDYSQWGQWSQVYGNPQQYGQYMANGWQVPP 335
            :   ||    |..|  .:|.||            ...::.......||| |..|....||
  Fly   193 D---VK----KALP--KQNDQQGGGGGRGGPGGRAGGNRGNMGGGNYGN-QNGGGNWNNG----- 242

Human   336 YGVYGQPWNQQGFGVDQSPSAAWMGGFG 363
                |..|.....|.|...:.::.||.|
  Fly   243 ----GNNWGNNRGGNDNWGNNSFGGGGG 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TIAL1	NP_001029097.1	RRM1_TIAR	10..107	CDD:410028	2/5 (40%)
		RRM2_TIAR	113..192	CDD:410029	23/81 (28%)
		RRM3_TIAR	222..294	CDD:241064	17/81 (21%)
Hrb98DE	NP_524543.1	RRM1_hnRNPA_like	32..109	CDD:409992	24/87 (28%)
		RRM_SF	123..195	CDD:473069	16/90 (18%)