Protein Alignment TIAL1 and lark

DIOPT Version :10

• Sequence 1: NP_001029097.1
• Gene: TIAL1 / 7073
• HGNCID: 11804
• Length: 392
• Species: Homo sapiens
• Sequence 2: NP_523957.1
• Gene: lark / 38811
• FlyBaseID: FBgn0011640
• Length: 352
• Species: Drosophila melanogaster
• Alignment Length: 275
• Identity: 64/275 - (23%)
• Similarity: 103/275 - (37%)
• Gaps: 67/275 - (24%)

Human   114 FHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQ 178
            |.:|:|:|..:....::::.|..:|.:.:..|||:        ||||....:....:||.::.|.
  Fly     7 FKLFIGNLDEKTQATELRALFEKYGTVVECDVVKN--------YGFVHMETEQQGRDAIQNLNGY 63

Human   179 WLGGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFS 243
            .|       |....|..|.||.:..||...:              ::.|.:........:|:.|.
  Fly    64 TL-------NEFAIKVEAAKSRRAPNTPTTK--------------IFVGNLTDKTRAPEVRELFQ 107

Human   244 PFGQIMEIRVFPEKGYSFVRFSTHESAAHAIVSVNGTTIEGHVVKCYWG----KESPDMTKNFQQ 304
            .:|.::|..:.  :.|.||..........||..:||..::|..:|....    :..|.|....|.
  Fly   108 KYGTVVECDIV--RNYGFVHLDCVGDVQDAIKELNGRVVDGQPLKVQVSTSRVRPKPGMGDPEQC 170

Human   305 VDYSQWGQWSQVYGNPQQYGQYMANGWQVPPYGVYGQPWNQQGFGVDQSPSAAWMGG-----FGA 364
            ....:.|.||:..  |:.||.  |.|.:.||                 ||.:|  ||     :|.
  Fly   171 YRCGRSGHWSKEC--PRLYGS--AGGGREPP-----------------SPLSA--GGYRDRMYGR 212

Human   365 QPPQGQAPPPVIPPP 379
            .|    .|||..|||
  Fly   213 DP----YPPPPPPPP 223

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TIAL1	NP_001029097.1	RRM1_TIAR	10..107	CDD:410028
		RRM2_TIAR	113..192	CDD:410029	18/77 (23%)
		RRM3_TIAR	222..294	CDD:241064	14/75 (19%)
lark	NP_523957.1	RRM1_2_CoAA_like	8..73	CDD:409779	18/79 (23%)
		RRM1_2_CoAA_like	87..152	CDD:409779	14/80 (18%)
		hnRNP-R-Q	<88..>258	CDD:273732	40/165 (24%)