DRSC/TRiP Functional Genomics Resources

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Protein Alignment TIAL1 and snRNP-U1-70K

DIOPT Version :10

Sequence 1:NP_001029097.1 Gene:TIAL1 / 7073 HGNCID:11804 Length:392 Species:Homo sapiens
Sequence 2:NP_477205.1 Gene:snRNP-U1-70K / 33982 FlyBaseID:FBgn0016978 Length:448 Species:Drosophila melanogaster


Alignment Length:190 Identity:39/190 - (20%)
Similarity:77/190 - (40%) Gaps:29/190 - (15%)


- Green bases have known domain annotations that are detailed below.


Human    25 ILQLFSQIGPCKSCKMITEQPDSRRVNSSVGFSVLQHTSNDPY-----CFVEFYE------HRDA 78
            :|.||:...|......:.:.|..::....:|.:.......||.     ..||..:      .|:.
  Fly     9 LLALFAAREPIPFMPPVDKLPHEKKSRGYLGVAKFMADFEDPKDTPLPKTVETRQERLERRRREK 73

Human    79 AAALAAMNGRKILGKEVKVNWATTPSSQKKDTSNHFH-VFVGDLSPEITTEDIKSAFAPFGKISD 142
            |..:|..     |.:|:.: |  .|:..|..|.:.|. :|:..::.:.:...::..|..:|.|..
  Fly    74 AEQVAYK-----LEREIAL-W--DPTEIKNATEDPFRTLFIARINYDTSESKLRREFEFYGPIKK 130

Human   143 ARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQI-------RT--NWATRK 193
            ..::.|..:||.|||.|:.:.::.|...|..|..|:.:..:::       ||  .|..|:
  Fly   131 IVLIHDQESGKPKGYAFIEYEHERDMHAAYKHADGKKIDSKRVLVDVERARTVKGWLPRR 190

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TIAL1NP_001029097.1 RRM1_TIAR 10..107 CDD:410028 17/92 (18%)
RRM2_TIAR 113..192 CDD:410029 19/88 (22%)
RRM3_TIAR 222..294 CDD:241064
snRNP-U1-70KNP_477205.1 U1snRNP70_N 3..92 CDD:432406 17/90 (19%)
RRM_snRNP70 101..188 CDD:409682 19/86 (22%)
Blue background indicates that the domain is not in the aligned region.

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