| Sequence 1: | NP_003239.2 | Gene: | THBS4 / 7060 | HGNCID: | 11788 | Length: | 961 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_775333.1 | Gene: | thbs4b / 252850 | ZFINID: | ZDB-GENE-020708-4 | Length: | 949 | Species: | Danio rerio |
| Alignment Length: | 952 | Identity: | 658/952 - (69%) |
|---|---|---|---|
| Similarity: | 762/952 - (80%) | Gaps: | 39/952 - (4%) |
- Green bases have known domain annotations that are detailed below.
|
Human 20 LAAGAQATPQVFDLLPSSSQRLNPGALLPVLTDPALNDLYVISTFKLQTKSSATIFGLYSSTDNS 84
Human 85 KYFEFTVMGRLNKAILRYLKNDGKVHLVVFNNLQLADGRRHRILLRLSNLQRG--------AGSL 141
Human 142 -----ELYLDCIQVDSVHNLPRAFAGPSQKPETIELRTFQRKPQDFLEELKLVVRGSLFQVASLQ 201
Human 202 DCFLQQSEPLAATGTGDFNRQFLGQMTQLNQLLGEVKDLLRQQVKETSFLRNTIAECQACGPLKF 266
Human 267 QSPTPSTVVPPAPPAPPTRPPRRCDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITCIDVDECK 331
Human 332 YHPCYPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECR---NGACVPNSI 393
Human 394 CVNTLGSYRCGPCKPGYTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDG 458
Human 459 YICGKDVDIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGDGILNEQDNC 523
Human 524 VLIHNVDQRNSDKDIFGDACDNCLSVLNNDQKDTDGDGRGDACDDDMDGDGIKNILDNCPKFPNR 588
Human 589 DQRDKDGDGVGDACDSCPDVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPTVINSAQLD 653
Human 654 TDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNSDGVGDICESDFDQDQVIDRIDV 718
Human 719 CPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEG 783
Human 784 TFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEH 848
Human 849 LRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYEGSELVADSGVTID 913
Human 914 TTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQTQN 955 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| THBS4 | NP_003239.2 | TSPN | 24..192 | CDD:214560 | 77/180 (43%) |
| coiled coil | 219..262 | CDD:293926 | 25/42 (60%) | ||
| TSP-4cc | 219..262 | CDD:293926 | 25/42 (60%) | ||
| EGF | 290..320 | CDD:278437 | 14/29 (48%) | ||
| EGF_CA | 326..360 | CDD:238011 | 23/33 (70%) | ||
| EGF_CA | 379..413 | CDD:238011 | 23/36 (64%) | ||
| TSP type-3 1 | 463..495 | 20/31 (65%) | |||
| TSP type-3 2 | 496..531 | 27/34 (79%) | |||
| TSP3 repeat_long | 496..531 | CDD:275366 | 27/34 (79%) | ||
| TSP_3 | 497..531 | CDD:280556 | 26/33 (79%) | ||
| TSP type-3 3 | 532..554 | 14/21 (67%) | |||
| TSP3 repeat_short | 532..554 | CDD:275366 | 14/21 (67%) | ||
| TSP type-3 4 | 555..590 | 25/34 (74%) | |||
| TSP3 repeat_long | 555..590 | CDD:275365 | 25/34 (74%) | ||
| Cell attachment site. /evidence=ECO:0000255 | 562..564 | 0/1 (0%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 579..672 | 80/92 (87%) | |||
| TSP3 repeat_short | 591..613 | CDD:275365 | 17/21 (81%) | ||
| TSP3 repeat_long | 614..651 | CDD:275365 | 33/36 (92%) | ||
| TSP_3 | 615..651 | CDD:280556 | 32/35 (91%) | ||
| TSP type-3 7 | 652..691 | 36/38 (95%) | |||
| TSP3 repeat_short | 652..691 | CDD:275366 | 36/38 (95%) | ||
| TSP type-3 8 | 692..727 | 28/34 (82%) | |||
| TSP3 repeat_long | 692..723 | CDD:275365 | 25/30 (83%) | ||
| TSP_3 | 693..726 | CDD:280556 | 28/32 (88%) | ||
| TSP_C | 745..942 | CDD:283408 | 190/196 (97%) | ||
| thbs4b | NP_775333.1 | LamG | <38..194 | CDD:304605 | 68/156 (44%) |
| TSPcc | 222..265 | CDD:300590 | 25/44 (57%) | ||
| coiled coil | 225..264 | CDD:293923 | 24/38 (63%) | ||
| EGF_CA | 312..346 | CDD:238011 | 23/33 (70%) | ||
| EGF_CA | 365..402 | CDD:238011 | 23/36 (64%) | ||
| TSP type-3 1 | 452..484 | 20/31 (65%) | |||
| TSP type-3 2 | 485..520 | 27/34 (79%) | |||
| TSP3 repeat_long | 485..520 | CDD:275366 | 27/34 (79%) | ||
| TSP_3 | 486..520 | CDD:280556 | 26/33 (79%) | ||
| TSP type-3 3 | 521..543 | 14/21 (67%) | |||
| TSP3 repeat_short | 521..543 | CDD:275366 | 14/21 (67%) | ||
| TSP type-3 4 | 544..579 | 25/34 (74%) | |||
| TSP3 repeat_long | 544..579 | CDD:275365 | 25/34 (74%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 578..672 | 83/93 (89%) | |||
| TSP3 repeat_short | 580..602 | CDD:275365 | 17/21 (81%) | ||
| TSP3 repeat_long | 603..640 | CDD:275365 | 33/36 (92%) | ||
| TSP_3 | 604..640 | CDD:280556 | 32/35 (91%) | ||
| TSP type-3 7 | 641..680 | 36/38 (95%) | |||
| TSP3 repeat_short | 641..680 | CDD:275366 | 36/38 (95%) | ||
| TSP type-3 8 | 681..716 | 28/34 (82%) | |||
| TSP3 repeat_long | 681..712 | CDD:275365 | 25/30 (83%) | ||
| TSP_3 | 682..715 | CDD:280556 | 28/32 (88%) | ||
| TSP_C | 734..931 | CDD:283408 | 190/196 (97%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C194329896 | |
| Domainoid | 1 | 1.000 | 412 | 1.000 | Domainoid score | I4331 |
| eggNOG | 1 | 0.900 | - | - | E1_2CMRF | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H20691 | |
| Inparanoid | 1 | 1.050 | 1381 | 1.000 | Inparanoid score | I1168 |
| NCBI | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG49685 | |
| OrthoDB | 1 | 1.010 | - | - | D120983at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0010787 | |
| OrthoInspector | 1 | 1.000 | - | - | oto47612 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_101187 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR10199 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R4962 |
| SonicParanoid | 1 | 1.000 | - | - | X995 | |
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 1 | 0.960 | - | - | ||
| ZFIN | 1 | 1.500 | - | - | ||
| 18 | 18.300 | |||||