DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rnf167 and DMA2

DIOPT Version :9

Sequence 1:	NP_081721.1	Gene:	Rnf167 / 70510	MGIID:	1917760	Length:	347	Species:	Mus musculus
Sequence 2:	NP_014283.3	Gene:	DMA2 / 855607	SGDID:	S000005060	Length:	522	Species:	Saccharomyces cerevisiae

Alignment Length:	131	Identity:	41/131 - (31%)
Similarity:	65/131 - (49%)	Gaps:	19/131 - (14%)

- Green bases have known domain annotations that are detailed below.

Mouse   183 LLVLAM----GTVLIVRCIQHRKRLQR------NRLTKEQLKQIPTHDYQK---GDEYDVCAICL 234
            :|.|.|    ||..|.||::.|..|.|      |...||.|:::  .:.||   |.|.:.|:|||
Yeast   375 ILQLGMDFRGGTEEIYRCVRMRIELNRSWKLKANSFNKEALQRL--QNLQKLTTGIEEEDCSICL 437

Mouse   235 DEYEDGDKLRVLPCAHAYHSRCVD--PWLTQTRKTCPICKQPVHRGPGDE--EQEEETQEQEEGD 295
            .:.:....:.:.||||::|.|||.  ..|:..:..||.|:.........|  ::|:|:..:.|||
Yeast   438 CKIKPCQAIFISPCAHSWHFRCVRRLVMLSYPQFVCPNCRSSCDLEASFESSDEEDESDVESEGD 502

Mouse   296 E 296
            :
Yeast   503 Q 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rnf167	NP_081721.1	PA_C_RZF_like	20..170	CDD:239038
		zf-RING_2	228..272	CDD:290367	15/45 (33%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	271..347		7/28 (25%)
DMA2	NP_014283.3	FHA	228..417	CDD:224630	15/41 (37%)
DMA2	NP_014283.3	RING-H2_Dmap_like	431..477	CDD:319372	15/45 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X670
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000