DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rnf167 and rnf167

DIOPT Version :9

Sequence 1:	NP_081721.1	Gene:	Rnf167 / 70510	MGIID:	1917760	Length:	347	Species:	Mus musculus
Sequence 2:	XP_005165694.2	Gene:	rnf167 / 101055497	ZFINID:	ZDB-GENE-110126-2	Length:	401	Species:	Danio rerio

Alignment Length:	348	Identity:	181/348 - (52%)
Similarity:	243/348 - (69%)	Gaps:	17/348 - (4%)

- Green bases have known domain annotations that are detailed below.

Mouse     7 PLPVVVATVLWGA---APVRGLIRATSEHNASMDFADLPALFGATLSDEGLQGFLVEAHPENACG 68
            ||.|.|..:::..   :|.:..|.|...:..||.|.|||||||:.|..:||.|.|:||.|:|||.
Zfish     7 PLAVSVLLIIFCTLVPSPGQAYIYAHYSNMTSMLFEDLPALFGSALPKDGLMGVLIEARPQNACT 71

Mouse    69 PIAPPPSAPV-----NGSVFIALLRRFDCNFDLKVLNAQKAGYGAAVVHNVNSNELLNMVWNSEE 128
            ||.|||::|.     :.:.:|.|:||:|||||:||.:||:|||.||:|||:.||.||||.:::|.
Zfish    72 PIDPPPASPTPADPNSTTKYIVLIRRYDCNFDVKVYHAQQAGYSAAIVHNMYSNSLLNMGYSNET 136

Mouse   129 IQQQIWIPSVFIGERSAEYLRALFVYEKGARVLLVPDNSFPLGYYLIPFTGIVGLLVLAMGTVLI 193
            |.::|.|||||....:::.|..: :.||||.|:|.|:.||||.||||||||:|.::::.|..::|
Zfish   137 IAEEISIPSVFTSFFASQMLHKI-IPEKGAYVVLKPEFSFPLSYYLIPFTGVVCMIIIVMVIIMI 200

Mouse   194 VRCIQHRKRLQRNRLTKEQLKQIPTHDYQKGDEYDVCAICLDEYEDGDKLRVLPCAHAYHSRCVD 258
            |||:||||||::|||:|||||:||.|.:.|||.||||||||||||:|||||||||:|||||||||
Zfish   201 VRCVQHRKRLRKNRLSKEQLKKIPIHKFNKGDSYDVCAICLDEYEEGDKLRVLPCSHAYHSRCVD 265

Mouse   259 PWLTQTRKTCPICKQPVHRGPGDEEQEEETQEQEEGDEGEPRD-QPASEWTPLLGSSPTLPTSFG 322
            ||||||:||||:|||.|.| |..|..|....::|.|    |.| :...|.||||  .|:.|.|..
Zfish   266 PWLTQTKKTCPVCKQRVTR-PNPEYSESSDSDEEAG----PHDAEEEDERTPLL--RPSNPGSPA 323

Mouse   323 SLAPAPLVFPGPSTDPSPPSSAA 345
            |.:|.|......:::|:..::||
Zfish   324 SSSPPPSYSSTVASEPATVTTAA 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rnf167	NP_081721.1	PA_C_RZF_like	20..170	CDD:239038	75/154 (49%)
		zf-RING_2	228..272	CDD:290367	39/43 (91%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	271..347		26/76 (34%)
rnf167	XP_005165694.2	PA_C_RZF_like	14..177	CDD:239038	75/163 (46%)
		RING-H2_RNF167	235..280	CDD:319711	40/44 (91%)
		RING-H2 finger (C3H2C3-type)	237..278	CDD:319711	37/40 (93%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	108	1.000	Domainoid score	I24222
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41046
Inparanoid	1	1.050	347	1.000	Inparanoid score	I8678
OMA	1	1.010	-	-		QHG51404
OrthoDB	1	1.010	-	-		D1487241at2759
OrthoFinder	1	1.000	-	-		FOG0001489
OrthoInspector	1	1.000	-	-		oto56295
orthoMCL	1	0.900	-	-		OOG6_103040
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R9031
SonicParanoid	1	1.000	-	-		X670
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	1	1.500	-	-
	14	14.410