Sequence 1: | NP_001121620.1 | Gene: | TFRC / 7037 | HGNCID: | 11763 | Length: | 760 | Species: | Homo sapiens |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_611414.1 | Gene: | CG10051 / 37222 | FlyBaseID: | FBgn0034437 | Length: | 866 | Species: | Drosophila melanogaster |
Alignment Length: | 576 | Identity: | 124/576 - (21%) |
---|---|---|---|
Similarity: | 185/576 - (32%) | Gaps: | 188/576 - (32%) |
- Green bases have known domain annotations that are detailed below.
Human 151 SYVPREAGSQKDE-NLALY---VENQFRE------------FKLSKVWRDQHFVKIQVKDSAQNS 199
Human 200 VIIVDKNGRLVYLVENPGGYVAYSKAATVTGKLVHANFGT----KKDFEDLYTPV----NGSIVI 256
Human 257 VRAGKITF---------AEKVANAESLNAIG--VLI------------YMDQTKFPIVN--AELS 296
Human 297 FFGH-----------------------AHLGTGDPYTPGFPSFNHTQFPPSRSSG---------L 329
Human 330 PNIPVQTISRAAAEK---LFGNMEGDCPSDWKTDSTCRMVTSESKNVKLTVSNVLKEIKILNIFG 391
Human 392 VIKGFVEPDHYVVVGAQRDAWGPGAAKSGVGTALLLKLAQMFSDM---------------VLKDG 441
Human 442 FQPSRSIIFASWSAGDFGSVGATEWLE-GYLSSLHL---KAFTYINLDKAVLGTSNFKVSASPLL 502
Human 503 YTL-IEKTMQNVK---HPVTGQFLYQDSNWASKVEKLTLDNAAF----------PFLAYSGI--- 550
Human 551 PAVSFCFCEDTDYPYLGTTMDTYKELIERIPELN---KVARAAAEVAGQFVIKLTH 603 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
TFRC | NP_001121620.1 | Mediates interaction with SH3BP4. /evidence=ECO:0000269|PubMed:16325581 | 1..67 | ||
Endocytosis signal. /evidence=ECO:0000269|PubMed:2298808 | 20..23 | ||||
Stop-transfer sequence. /evidence=ECO:0000303|PubMed:6090955 | 58..61 | ||||
PA_TfR | 201..377 | CDD:239043 | 46/243 (19%) | ||
M28_TfR | 385..610 | CDD:193572 | 58/258 (22%) | ||
Ligand-binding | 569..760 | 9/38 (24%) | |||
TFR_dimer | 642..750 | CDD:282153 | |||
Cell attachment site, required for binding to transferrin | 646..648 | ||||
CG10051 | NP_611414.1 | M28_Fxna_like | 62..369 | CDD:193497 | 62/299 (21%) |
MATE_like | 361..>604 | CDD:298879 | 64/290 (22%) | ||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_COG2234 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 0 | 0.000 | Not matched by this tool. | |||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
1 | 0.900 |