Protein Alignment TFPI and tag-290

DIOPT Version :9

• Sequence 1: NP_001316168.1
• Gene: TFPI / 7035
• HGNCID: 11760
• Length: 304
• Species: Homo sapiens
• Sequence 2: NP_505945.1
• Gene: tag-290 / 179593
• WormBaseID: WBGene00009386
• Length: 219
• Species: Caenorhabditis elegans
• Alignment Length: 251
• Identity: 60/251 - (23%)
• Similarity: 100/251 - (39%)
• Gaps: 60/251 - (23%)

Human    36 HTIITDTELPPLKLMHSF-CAFKADDG-PCKAIM--KRFFFNIFTRQCEEFIYGGCEGNQNRFES 96
            |.::....:|    :.|| |....|.| .|....  :.|:|:...:.|:.|:|.||.||:|||.:
 Worm     4 HLLVCVLLVP----VFSFDCTQPKDSGNVCSGSQAERSFYFDTRMKVCQPFLYSGCGGNENRFST 64

Human    97 LEECKKMCTRDNANRIIKTTLQQEKPDFCFLEEDPGICRG------YITRYFYNNQTKQCERFKY 155
            .:||:..|...      |::...|.||  .:.:|.....|      ::.:...::|.::.:
 Worm    65 SKECRDACQNK------KSSSTTESPD--TISDDSADQSGSPNSPPFVPQGDGHDQWRKAD---- 117

Human   156 GGCLGNMNNFETLEECKNICEDG---PNGFQVDNYGTQL-----NAVNNSLTPQSTKVPSLFEFH 212
                              ||...   |||..:.....|.     :.||.:..|....|.||.:.:
 Worm   118 ------------------ICGSNYLIPNGKYITCSPNQACPKFHSCVNGACCPSKDYVCSLRDDN 164

Human   213 GPSWCLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRACK 268
            | |:.....||       .||.:|:.:..|..:.|.|..||.|||.:.|.|::.|:
 Worm   165 G-SFMDGVEDR-------PRFSWNNDVHSCTRWSYYGANGNYNNFPNFQSCMKFCQ 212

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TFPI	NP_001316168.1	Kunitz_BPTI	53..104	CDD:278443	19/54 (35%)
		KU	123..175	CDD:238057	4/57 (7%)
		Kunitz_BPTI	216..268	CDD:278443	15/51 (29%)
tag-290	NP_505945.1	Kunitz_BPTI	19..73	CDD:278443	18/53 (34%)
		KU	156..211	CDD:197529	20/62 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4295
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	71	1.000	Inparanoid score	I4351
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000145
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.860